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GenomicsGenome-wide survey of YY1 targets in C2C12 cells by High-throughput sequencing
By applying ChIP-seq, we generated genome-wide maps of YY1 in skeletal myoblasts and myotubes. We found that YY1 binds to 1820 confident target with a large portion residing in the intergenic regions. In addition, YY1 was found to activate many loci, and there is no significant overlap between YY1 a...
ORGANISM(S): Mus musculus 
2013-08-15 | E-GEOD-45875 | biostudies-arrayexpress
TranscriptomicsRegulatory mechanisms on the early process of mouse spermatogenesis investigated by digital gene expression tag profiling analysis
A detailed understanding of the gene regulation mechanisms in premeiosis cells is germane to understanding normal spermatogenesis. The genome-wide expression profiles of type B spermatogonia and primary spermatocytes in mouse were investigated using Solexa/Illumina’s digital gene expression (DGE) sy...
ORGANISM(S): Mus musculus 
2015-06-20 | E-GEOD-38845 | biostudies-arrayexpress
Proteomicsproteome and phosphoproteome profiling of nonsmall cell lung cancer cells treated by TRAIL
tumor necrosis factor-related apoptosis-inducing liagand is one of the promising cancer therapeutic, however, many tumors have developed different degrees of drug resistance during TRAIL treatment. the mechanism by which is unvlear, and here we reasoned that systematic proteomic and phosphoproteomic...
ORGANISM(S): Homo Sapiens 
2022-06-06 | PXD034338 |
TranscriptomicsIntegrative Analysis of Transcriptomic and Epigenomic Data to Reveal Regulation Patterns for Osteoporosis Risk [miRNA]
In this study, we analyzed transcriptome gene expression microarray, epigenomic miRNA microarray and methylome sequencing data simultaneously in PBMs from 5 high hip BMD subjects and 5 low hip BMD subjects. Through integrating the transcriptomic and epigenomic data, firstly we identified BMD-related...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-63446 | biostudies-arrayexpress
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