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TranscriptomicsIntegrated molecular genetic profiling of pediatric-high grade gliomas reveals key differences with adult disease
Purpose: To define copy number alterations and gene expression signatures underlying pediatric high-grade glioma (HGG). Patients and Methods: We conducted a high-resolution analysis of genomic imbalances in 78 de novo pediatric HGG, including 7 diffuse intrinsic pontine gliomas, and 10 HGG cases ar...
ORGANISM(S): Homo sapiens 
2010-06-15 | E-GEOD-19578 | biostudies-arrayexpress
GenomicsWhole genome sequencing of tumour and normal paired samples of diffuse intrinsic pontine gliomas
Diffuse intrinsic pontine glioma (DIPG) have a universally dismal prognosis (median 9-12 months), with neither chemotherapeutic nor targeted agents showing any substantial survival benefit in clinical trials in children with these tumours. DIPG are highly infiltrative malignant glial neoplasms of th...
EGAS00001000572 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:22:20:271-113 - samples
Whole exome sequencing of 6 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000706 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:02:33:112-168 - samples
Whole genome sequencing of 20 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000705 | EGA
GenomicsICR DIPG Data Access Committee
Data Access Committee EGAC00001000148
EGAC00001000148 | EGA
TranscriptomicsComparative genomic hybridization of high grade gliomas arising in children and young people
As genome-scale technologies begin to unravel the complexity of the equivalent tumours in adults, detailed characterisation of high grade gliomas in children have until recently been lacking. In order to validate and extend investigations of the differences between paediatric and adult tumours, we c...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-TABM-857 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of Malignant Rhabdoid Tumours
An observational experiment to methylation profile 79 SMARCB1 negative primary tumours from patients diagnosed with Malignant Rhabdoid Tumours.
ORGANISM(S): Homo sapiens 
2020-07-15 | E-MTAB-6708 | biostudies-arrayexpress
TranscriptomicsExpression profiling following SMARCB1 re-expression in MRT cell lines time course over 14 days
MRT cell lines KD, SWOH, LM, DEV and G401 were expression profiled following SMARCB1 re-expression using a lentivirus. Samples were taken at Day 0,1,3,7 and 14 and compared to empty vector control experiments.
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-6674 | biostudies-arrayexpress
UnknownClinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.
Not available
S-EPMC6075859 | biostudies-literature
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