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MetabolomicsImpact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository

INTRODUCTION: Acute lymphoblastic leukemia (ALL) is among the most common cancers in children. With improvements in combination chemotherapy regimens, the overall survival has increased to over 90%. However, the current challenge is to mitigate adverse events resulting from the c...

2021-08-12 | MTBLS2394 | MetaboLights
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS382 | MetaboLights
ProteomicsSILAC analysis of ptp-3 knockout in C. elegans
A ptp-3 mutant and wildtype C. elegans were SILAC labeled and subjected to whole proteome analysis and phosphotyrosine enrichment.
ORGANISM(S): Caenorhabditis elegans 
2016-12-14 | PXD003233 | Pride
Phosoproteomics C. elegans Silac 
UnknownIndependent evaluation of Wolbachia infected male mosquito releases for control of Aedes aegypti in Harris County, Texas, using a Bayesian abundance estimator.
Not available
S-EPMC9704758 | biostudies-literature
TranscriptomicsRegulation of gene expressions in vivo by anti-VEGF therapy
U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, when tumour is established in BALB/c SCID mice. At the end point, collect tumour samples and extracted total RNA for microarray to investigate the gene profile changes compared to ...
ORGANISM(S): Homo sapiens 
2014-04-25 | E-GEOD-37956 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expressions in vivo by anti-VEGF and anti-Notch therapy [Mouse430_2]
U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, or dibenzazepine (DBZ) when tumour is established in BALB/c SCID mice. At the end point, collect tumour samples and extracted total RNA for microarray to investigate the gene profi...
ORGANISM(S): Mus musculus 
2014-04-25 | E-GEOD-39413 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expressions in vivo by anti-VEGF and anti-Notch therapy [HG-U133_Plus_2]
U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, or dibenzazepine (DBZ), when tumour is established in BALB/c SCID mice. At the end point, collect tumour samples and extracted total RNA for microarray to investigate the gene prof...
ORGANISM(S): Homo sapiens 
2014-04-25 | E-GEOD-39223 | biostudies-arrayexpress
TranscriptomicsRole of SPI-1 Secreted Effectors, SipA, SopABDE2, in Acute Bovine Response to Salmonella enterica Serovar Typhimurium
Salmonella enterica Serovar Typhimurium (S. Typhimurium) causes enterocolitis in humans and calves characterized by diarrhea and polymorphonuclear cell (PMN) influx to the intestinal mucosa. The Salmonella Type III Secretion System encoded at Pathogenicity Island I (SPI-1) translocates the Salmonel...
ORGANISM(S): Bos taurus 
2012-01-10 | E-GEOD-13847 | biostudies-arrayexpress
TranscriptomicsExpression profiling of MRC5 senescent fibroblasts
Microarrays analysis identifies WNT16in senescent fibroblasts. To identify genes expressed in replicative senescence, microarray experiments were conducted in which we compared the RNA expression profile of young MRC5 fibroblasts at population doubling 28 (PDL28) and replicative senescent MRC5 fibro...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-15919 | biostudies-arrayexpress
UnknownPersistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias.
Not available
S-EPMC4876110 | biostudies-literature
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