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ProteomicsAccumulation of acylcarnitines and mitochondrial dysfunction characterize the loss of neonatal myocardial regeneration capacity
Myocardial regeneration capacity declines during the first week after birth and is linked to the adaptation to oxidative metabolism. Utilizing this regenerative window, we characterized the metabolic changes in myocardial injury in 1-day-old regeneration-competent and 7-day-old regeneration-compromi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-04 | MSV000088783 | MassIVE
GenomicsTaf7l cooperates with Trf2 to regulate spermiogenesis
Taf7l (a paralogue of Taf7) and Trf2 (a TBP-related protein) are components of the core promoter complex required for gene/tissue-specific transcription of protein-coding genes by RNA polymerase II. Previous studies reported that Taf7l knockout mice exhibit structurally abnormal sperm, reduced sperm...
ORGANISM(S): Mus musculus 
2013-09-29 | E-GEOD-50807 | biostudies-arrayexpress
UnknownADT-1004: a first-in-class, oral pan-RAS inhibitor with robust antitumor activity in preclinical models of pancreatic ductal adenocarcinoma.
Not available
S-EPMC11905721 | biostudies-literature
GenomicsDual Functions of TAF7L in Adipocyte Differentiation
The diverse transcriptional mechanisms governing cellular differentiation and development of mammalian tissue remains poorly understood. Here we report that TAF7L, a paralogue of TFIID subunit TAF7, is enriched in adipocytes and mouse white fat tissue (WAT). Depletion of TAF7L reduced adipocyte-spec...
ORGANISM(S): Mus musculus 
2013-01-07 | E-GEOD-41937 | biostudies-arrayexpress
UnknownElective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries.
Not available
S-EPMC9621702 | biostudies-literature
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