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UnknownPhase I study of a novel oral Janus kinase 2 inhibitor, SB1518, in patients with relapsed lymphoma: evidence of clinical and biologic activity in multiple lymphoma subtypes.
Not available
S-EPMC5950499 | biostudies-literature
TranscriptomicsP493-6 treated with KJ-Pyr-9 and/or Doxycycline
In a fluorescence polarization screen for MYC-MAX interaction, we have identified a novel small molecule inhibitor of MYC, KJ-Pyr-9, from a Kröhnke pyridine library. The Kd of KJ-Pyr-9 for MYC in vitro is 6.5 ± 1.0 nM as determined by backscattering interferometry; KJ-Pyr-9 also interferes with MYC-...
ORGANISM(S): Homo sapiens 
2014-08-25 | E-GEOD-58168 | biostudies-arrayexpress
UnknownRetinal-glia ischemia and inflammation induced by chronic stress: The SABPA study.
Not available
S-EPMC8474432 | biostudies-literature
UnknownDevelopment of Macrocyclic PRMT5-Adaptor Protein Interaction Inhibitors.
Not available
S-EPMC9706563 | biostudies-literature
ProteomicsImpact of Sample Preparation Strategies on The Quantitative Accuracy of Low-Abundance Serum Proteins in Shotgun Proteomics
Serum proteomics plays a crucial role in biomarker discovery and disease research, yet the selection of an optimal sample preparation method remains challenging. Evaluating the accuracy of protein quantitation is of major importance and a vital part of a benchmarking study in proteomics, since clini...
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD062785 | Pride
Reproducibility Quantitative accuracy Serum proteomics Depth of coverage 
TranscriptomicsTranscription profiling of human skeletal muscle samples from geriatric and pediatric individuals
There is a consistent variation in the response of different skeletal muscle groups to mutations in genes known to cause muscular dystrophy, yet these muscles appear histologically similar. To better understand these phenotypic differences, we analyzed gene expression patterns in control muscle spec...
ORGANISM(S): Homo sapiens 
2007-07-03 | E-GEOD-4667 | biostudies-arrayexpress
UnknownInherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.
Not available
S-EPMC4302212 | biostudies-literature
UnknownEpithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments.
Not available
S-EPMC5037318 | biostudies-literature
UnknownBRCA1/2 Mutations and Bevacizumab in the Neoadjuvant Treatment of Breast Cancer: Response and Prognosis Results in Patients With Triple-Negative Breast Cancer From the GeparQuinto Study.
Not available
S-EPMC6067803 | biostudies-literature
TranscriptomicsHigh-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
The ability to perturb genes in human cells is crucial for elucidating gene function and holds great potential for finding therapeutic targets for diseases such as cancer. To extend the catalog of human core and context- dependent fitness genes, we have developed a high-complexity second-generation ...
ORGANISM(S): Homo sapiens 
2015-11-25 | E-GEOD-75189 | biostudies-arrayexpress
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