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GenomicsVirulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein
The principal virulence determinant of Mycobacterium tuberculosis (Mtb), the ESX-1 protein secretion system, is positively controlled at the transcriptional level by EspR. Depletion of EspR reportedly affects a small number of genes, both positively or negatively, including a key ESX-1 component, th...
ORGANISM(S): Mycobacterium tuberculosis 
2012-04-02 | E-GEOD-35149 | biostudies-arrayexpress
TranscriptomicsGenome-wide Definition of the SigF Regulon in Mycobacterium tuberculosis
This SuperSeries is composed of the following subset Series: GSE34919: Genome-wide Definition of the SigF Regulon in Mycobacterium tuberculosis (ChIP-chip) GSE34922: Genome-wide Definition of the SigF Regulon in Mycobacterium tuberculosis (Expression) Refer to individual Series
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2012-01-20 | E-GEOD-35080 | biostudies-arrayexpress
TranscriptomicsGenome-wide Definition of the SigF Regulon in Mycobacterium tuberculosis (ChIP-chip)
The genome wide ChIP-on-chip analysis to identify the DNA binding sites for the M.tuberculosis sigma factor Rv3286c (SigF) SigF binding sites were determined by microarray analysis of anti-sigF immunoprecipitated DNA from H37Rv(ΔrsbW/sigF)::pmySigF compared to H37Rv(ΔrsbW/sigF)::pMY769 (both cultur...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2012-01-20 | E-GEOD-34919 | biostudies-arrayexpress
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