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ModelsIancu2007_CardiacMyoscytes_cAMPsignaling
This a model from the article: Compartmentation of cAMP signaling in cardiac myocytes: a computational study. Iancu RV, Jones SW, Harvey RD. Biophys J 2007 May 1;92(9):3317-31 17293406 , Abstract: Recepto...
2005-01-01 | MODEL1006230117 | BioModels
TranscriptomicsRegulation of Mouse Lens Development and Gene Expression by Krüppel-Like Factor 4
Conditional disruption of Klf4 in the ectoderm-derived tissues of the eye results in defective cornea, conjunctiva and the lens. Expression of Klf4 is first detected in the embryonic day-12 (E12) mouse lens, peaks at E16, and declines thereafter. Lenses from Mice which were conditional null for Klf4...
ORGANISM(S): Mus musculus 
2013-07-01 | E-GEOD-47694 | biostudies-arrayexpress
TranscriptomicsResponse of human corneal epithelial cells to the secretomes of wild-type Serratia marcescens and an eepR mutant strain
The bacterium Serratia marcescens is a common contaminant of contact lens cases and lenses. Serratamolide is one of the secreted hemolytic/cytotoxic factors which contribute to the virulence of this opportunistic pathogen (PMID 22615766). A newly identified transcription factor (eepR) is essential ...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-71320 | biostudies-arrayexpress
ProteomicsA dataset describing a suite of novel antibody reagents for the RAS signaling network
RAS genes are frequently mutated in cancer and have for decades eluded effective therapeutic attack. The National Cancer Institute’s RAS Initiative has a focus on understanding pathways and discovering therapies for RAS-driven cancers. Part of these efforts is the generation of novel reagents to ena...
ORGANISM(S): Homo Sapiens 
PXD012604 | panorama
TranscriptomicsHigh-throughput gene expression profiling of Salmonella enterica serovar Paratyphi A in the blood of bacteremic patients in Bangladesh
In this work, we applied an RNA analysis method, Selective Capture of Transcribed Sequences (SCOTS), and cDNA hybridization-microarray technology to identify S. Paratyphi A transcripts expressed by bacteria in the blood of three patients in Bangladesh. In total, we detected 1798 S. Paratyphi A mRNA...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Paratyphi A 
2010-09-06 | E-GEOD-22958 | biostudies-arrayexpress
TranscriptomicsmRNA Sequencing Reveals Altered Synaptic Vesicular Transport in Post-Mortem Cerebellum
Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we generated 16.7 billion nucleotides of short read, shotgun sequences of cDNA from post-mortem cerebellar c...
ORGANISM(S): Homo sapiens 
2009-08-29 | E-GEOD-12297 | biostudies-arrayexpress
UnknownPostinduction dexamethasone and individualized dosing of Escherichia Coli L-asparaginase each improve outcome of children and adolescents with newly diagnosed acute lymphoblastic leukemia: results from a randomized study--Dana-Farber Cancer Institute ALL Consortium Protocol 00-01.
Not available
S-EPMC3595424 | biostudies-literature
TranscriptomicsThe transcriptomic response of rat hepatic stellate cells to endotoxin: implications for hepatic inflammation and immune regulation
Located in the perisinusoidal space of Disse, hepatic stellate cells (HSCs) communicate with all other liver cell types by physical association and / or by producing cytokines and chemokines. In liver disease and folllowing liver transplantation, elevated levels of endotoxin (bacterial lipopolysacch...
ORGANISM(S): Rattus norvegicus 
2013-10-31 | E-GEOD-49980 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human vastus lateralis biopsies from healthy young (20-29 years old) or older (65-75 years old) adults
vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old)
ORGANISM(S): Homo sapiens 
2007-12-13 | E-GEOD-362 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat resistance artery in 2 models of hypertension
We investigated morphometric structure and gene expression by microarray analysis in a small diameter artery, branch of the saphenous artery (a resistance artery), in representative models of renin-angiotensin system (RAS)-dependent and glucocorticoid hypertension, using the spontaneously hypertensi...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-8051 | biostudies-arrayexpress
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