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MetabolomicsHistidine improves Hashimoto thyroiditis by inhibiting the production of Neutrophil Txtracellular Traps

Objective: Metabolite abnormalities are potentially implicated in pathogenesis of Hashimoto’s thyroiditis (HT). An in-depth study of the relationship between HT and small molecule metabolites, as well as its pathogenesis, can help enhance the diagnosis, prognosis, and treatment of HT patients.

2025-10-12 | MTBLS12333 | MetaboLights
MetabolomicsAlterations in the amino acid profile in patients with papillary thyroid carcinoma with and without Hashimoto’s thyroiditis

PURPOSE: Amino acids (AAs) play important physiological roles in living cells. Some amino acid changes in blood are specific for autoimmune disorders, and some are specific for thyroid cancer. The aims of this study were to profile AA metabolites in the serum of patients with pap...

2023-08-09 | MTBLS8012 | MetaboLights
ProteomicsProteomics and Organoid Culture Reveal the Underlying Pathogenesis of Hashimoto's Thyroiditis
To understand Hashimoto's Thyroiditis and translate this knowledge to clinical applications, we took mass spectrometric analysis on thyroid tissue fine-needle puncture from HT patients and healthy people in an attempt to make a further understanding of the pathogenesis of Hashimoto's Thyroiditis.
ORGANISM(S): Homo Sapiens 
2021-09-10 | PXD028448 |
GenomicsSpatial transcriptome gene expression profile in 2 patients with Hashimoto's thyroiditis and 2 patients with papillary thyroid cancer combined with Hashimoto's thyroiditis.
Spatial transcriptome gene expression profile in 2 patients with Hashimoto's thyroiditis and 2 patients with papillary thyroid cancer combined with Hashimoto's thyroiditis.
PRJNA961115 | ENA
GenomicsCirculating microRNA expression profiling of Hashimoto's Thyroiditis
Circulating microRNA expression profiling of Hashimoto's Thyroiditis
PRJNA623358 | ENA
GenomicsCirculating LncRNA expression profiling of Hashimoto's Thyroiditis
Circulating LncRNA expression profiling of Hashimoto's Thyroiditis
PRJNA658064 | ENA
TranscriptomicsPrimary peripheral T-cell lymphoma, not otherwise specified of the thyroid with autoimmune thyroiditis
Comprehensive gene expression profiles of four Primary T-cell lymphomas of the thyroid were analyzed to detect tumor-specific genes. The gene expression profiles of CD4 positive T-lymphocytes from normal donor were analyzed as control samples.
ORGANISM(S): Homo sapiens 
2013-02-15 | E-MTAB-1411 | biostudies-arrayexpress
TranscriptomicsHuman papillary thyroid carcinoma landscape and its immunological link with Hashimoto's thyroiditis at single cell resolution
Tumor microenvironment heterogeneity sheltered our understanding of papillary thyroid cancer. However, molecular characteristics of papillary thyroid cancer has not been reported at single cell resolution. The immunological link between papillary thyroid cancer and Hashimoto's thyroiditis is also in...
ORGANISM(S): Homo sapiens 
2021-07-01 | GSE163203 | GEO
TranscriptomicsSpatial transcriptome gene expression profile in 2 patients with Hashimoto's thyroiditis and 2 patients with papillary thyroid cancer combined with Hashimoto's thyroiditis.
Hashimoto's thyroiditis and papillary thyroid cancer are the most common thyroid disorders. We used spatial transcriptome sequencing (ST-seq) to investigate their potential relationship.
ORGANISM(S): Homo sapiens 
2024-06-27 | GSE230424 | GEO
GenomicsHuman papillary thyroid carcinoma landscape and its immunological link with Hashimoto's thyroiditis at single cell resolution
Human papillary thyroid carcinoma landscape and its immunological link with Hashimoto's thyroiditis at single cell resolution
PRJNA685185 | ENA
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