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ProteomicsInhibition of T cell activation and function by the CIN85 adaptor protein
CIN85 is ubiquitously expressed adaptor protein. In T cells, CIN85 is recruited to the TCR signaling complex and inhibit TCR signaling. To reveal the molecular function of CIN85-mediated inhibition, we performed Flag-CIN85 (CIN85dA) immuno-precipitation and identified the binding proteins. As a nega...
ORGANISM(S): Mus Musculus (mouse) 
2019-01-16 | PXD012369 | JPOST Repository
ProteomicsDIA-MS based proteome analysis of HL-60 cells treated with new anti-cancer drug (TAS4464)
We investigated the protein change of HL-60 cells with TAS4464 treatment in time series (0 h, 1h, 4h, 8h, 16h, 24h) by overlapping DIA-MS based proteome analysis. Spectral library was created by analyzing pooled samples by five gas-phase fractionated overlapping DIA-MS measurements.
ORGANISM(S): Homo Sapiens (human) 
2021-08-20 | PXD021012 | JPOST Repository
UnknownGenomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p.
Not available
S-EPMC1285184 | biostudies-literature
ProteomicsPCGF1-PRC1 safeguards recovery of nucleosome positioning during S-phase to ensure early hematopoiesis
Polycomb repressive complexes 1 and 2 (PRC1 and 2) repress lineage inappropriate genes during development to maintain proper cellular identities. To reveal the function of a variant PRC1 containing PCGF1 (PCGF1-PRC1), we prepared PCGF1 interacting proteins by immunoprecipitation and characterized th...
ORGANISM(S): Mus Musculus (mouse) 
2023-05-13 | PXD033883 | JPOST Repository
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