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GenomicsDistinct roles of Haspin in stem cell division and male gametogenesis
Distinct roles of Haspin in stem cell division and male gametogenesis
PRJNA645564 | ENA
GenomicsHaspin regulates mouse embryonic stem cell developmental potencies through Wnt5a mediated asymmetric cell division
Haspin regulates mouse embryonic stem cell developmental potencies through Wnt5a mediated asymmetric cell division
PRJNA911679 | ENA
TranscriptomicsHaspin regulates mouse embryonic stem cell developmental potencies through Wnt5a mediated asymmetric cell division
To investigate the function of Haspin in the mouse embryonic stem cell, we established Haspin knockout cell lines.
ORGANISM(S): Mus musculus 
2023-08-30 | GSE220824 | GEO
TranscriptomicsDistinct roles of Haspin in stem cell division and male gametogenesis
The atypical protein kinase Haspin phosphorylates Histone H3 at threonine-3 (H3T3ph) during mitosis. H3T3ph creates a docking site for the Chromosomal Passenger Complex at the inner centromere, enabling correction of erratic microtubule-chromosome contacts and preventing chromosome mis-segregation. ...
ORGANISM(S): Mus musculus 
2021-10-06 | GSE154246 | GEO
GenomicsTargeting HASPIN kinase disrupts SR protein-mediated RNA splicing and synergizes with BCL-2 inhibitor venetoclax in AML
Targeting HASPIN kinase disrupts SR protein-mediated RNA splicing and synergizes with BCL-2 inhibitor venetoclax in AML
PRJNA1183348 | ENA
GenomicsGenomic distribution of the cohesin subunit Stromalin (SA) in wild-type and Haspin knock-down Drosophila melanogaster Kc167 cells
Genomic distribution of the cohesin subunit Stromalin (SA) in wild-type and Haspin knock-down Drosophila melanogaster Kc167 cells
PRJNA551978 | ENA
UnknownHaspin kinase binds to a nucleosomal DNA supergroove.
Not available
S-EPMC12170164 | biostudies-literature
TranscriptomicsTargeting HASPIN kinase disrupts SR protein-mediated RNA splicing and synergizes with BCL-2 inhibitor venetoclax in AML
Acute Myeloid Leukemia (AML) is a blood cancer complicated by acquired drug resistance, disease relapse, and low overall survival rates. Combination therapies using multiple targeted inhibitors can effectively treat AML patients. However, combination treatments are limited by the number of useable t...
ORGANISM(S): Homo sapiens 
2025-08-04 | GSE281301 | GEO
UnknownModulation of the chromatin phosphoproteome by the Haspin protein kinase.
Not available
S-EPMC4083111 | biostudies-literature
UnknownHaspin kinase modulates nuclear architecture and Polycomb-dependent gene silencing.
Not available
S-EPMC7428214 | biostudies-literature
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