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GenomicsATRX-mediated chromatin association of histone variant macroH2A1 regulates alpha globin gene expression
The histone variant macroH2A generally associates with transcriptionally inert chromatin, however the factors that regulate its chromatin incorporation remain elusive. Here, we identify the SWI/SNF helicase, ATRX, as a novel macroH2A interacting protein. Unlike its role in assisting H3.3 chromatin d...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-35339 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human centromeric protein A, histone3 K4 and K9 modifications, HP1a and HP1g
Chromatin Immunoprecipitation of centromeric protein A, histone3 K4 and K9 modifications, HP1a and HP1g
ORGANISM(S): Homo sapiens 
2010-02-27 | E-TABM-705 | biostudies-arrayexpress
GenomicsHistone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma [native ChIP-seq]
Here we report a novel role for H2A.Z.2 (H2AFV) as a mediator of cell proliferation and sensitivity to targeted therapies in malignant melanoma. While both H2A.Z.1 and H2A.Z.2 are highly expressed in metastatic melanoma and correlate with decreased patient survival, only H2A.Z.2 deficiency results i...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-68222 | biostudies-arrayexpress
TranscriptomicsFormation of novel CENP-A domains on tandem repetitive DNA and across chromosome
Chromatin Immunoprecipitation of Centromeric Protein A. (Note WIG and CHP files are available in the additional.zip archive)
ORGANISM(S): Homo sapiens 
2011-03-01 | E-TABM-1098 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of centromeric proteins CenpA, CenpC and CenpH from human cell lines which contain either a neocentromere in band 13q21 or no neocentric chromosome
Chromatin Immunoprecipitation of Centromeric Proteins, CenpA, CenpC or CenpH from cell lines which contain either a neocentromere in band 13q21 or no neocentric chromosomes

Processed data files with additional statistics are available for download from
ORGANISM(S): Homo sapiens 
2008-03-22 | E-TABM-257 | biostudies-arrayexpress
GenomicsmacroH2A histone variants act as a barrier upon reprogramming towards pluripotency
Here we report that the histone variant macroH2A acts as a barrier to induced pluripotency. Using fibroblasts isolated from macroH2A double knockout mice, we observed enhanced reprogramming efficiency compared to fibroblasts from wild type animals. We further show that macroH2A isoforms act synergis...
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-40813 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of centromeric proteins CenpC and CenpH from human cell lines containing a neocentromere in band 13q32
Chromatin Immunoprecipitation of Centromeric Proteins, CenpA, CenpC or CenpH from human cell lines containing a neocentromere in band 13q32

Processed data files with additional statistics are available for download from
ORGANISM(S): Homo sapiens 
2008-03-22 | E-TABM-238 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of centromeric proteins CenpA, CenpC and CenpH from human cell line BBB, which contains a neocentromere in band 13q33.1
Chromatin Immunoprecipitation of Centromeric Proteins, CenpA, CenpC or CenpH from cell line BBB, which contains a neocentromere in band 13q33.1

Processed data files with additional statistics are available for download from
ORGANISM(S): Homo sapiens 
2008-03-22 | E-TABM-245 | biostudies-arrayexpress
UnknownBone-Induced HER2 Promotes Secondary Metastasis in HR+/HER2- Breast Cancer.
Not available
S-EPMC11964846 | biostudies-literature
TranscriptomicsHistone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma (expression)
Here we report a novel role for H2A.Z.2 (H2AFV) as a mediator of cell proliferation and sensitivity to targeted therapies in malignant melanoma. While both H2A.Z.1 and H2A.Z.2 are highly expressed in metastatic melanoma and correlate with decreased patient survival, only H2A.Z.2 deficiency results i...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-59026 | biostudies-arrayexpress
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