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UnknownData integration workflow for search of disease driving genes and genetic variants.
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S-EPMC3075259 | biostudies-literature
TranscriptomicsTranscription profiling by array of submandibular salivary glands from PAP knockout and wild type mice
Prostatic acid phosphatase is the main acid phosphatase in mouse submandibular salivary gland
ORGANISM(S): Mus musculus 
2014-04-15 | E-MTAB-2099 | biostudies-arrayexpress
TranscriptomicsDisrupted interaction of transmembrane prostatic acid phosphatase and snapin will lead to prostate cancer
Disrupted interaction of transmembrane prostatic acid phosphatase and snapin will lead to prostate cancer
ORGANISM(S): Mus musculus 
2013-09-12 | E-MTAB-1191 | biostudies-arrayexpress
GenomicsTissue-specific pioneer factors associate with androgen receptor cistromes and transcription programs. [ChIP-Seq]
We report the in vivo androgen receptor (AR) binding sites in murine prostate, epididymis and kidney in response to physiological androgen testosterone using ChIP-sequencing and gene expression profiling by microarray. From AR cistrome analysis, we identified tissue-specific collaborating factors i....
ORGANISM(S): Mus musculus 
2014-01-21 | E-GEOD-47192 | biostudies-arrayexpress
TranscriptomicsFoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells (mRNA)
We report the androgen receptor recruitment to the chromatin of androgen responsive prostate cancer cell lines, LNCaP-1F5 and VCaP in response to physiological androgen 5a-dihydrotestosterone (DHT) using ChIP-sequencing. We compare the AR recruitment by DHT to that by partial agonist/antagonist cypr...
ORGANISM(S): Homo sapiens 
2013-02-05 | E-GEOD-39654 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Hela CD4+ cells transfected with epitope tagged eTat or parental vector to identify therapeutic targets for HIV-1 infection in the host proteome.
Despite the success of Highly Active Anti-Retroviral Therapy (HAART), patients often stop treatment due to the inception of side effects. Furthermore, viral resistance often develops, making one or more of the drugs ineffective. Identification of novel targets for therapy that may not develop resist...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-6431 | biostudies-arrayexpress
TranscriptomicsTranscrioptome analysis of human primary macrophages stimulated by bacterial endotoxin lipopolysaccharide (LPS), and (1,3)-b-glucans, curdlan and glucan from bakerM-BM-4s yeast (GBY)
We performed gene expression microarray experiments to compare the global transcriptional response induced by b-glucans and LPS with their secretomes. We identified 1683, 767 and 1447 genes with over two-fold increase or decrease in LPS-, curdlan- or GBY-stimulated macrophages, respectively. We show...
ORGANISM(S): Homo sapiens 
2014-05-15 | E-GEOD-32282 | biostudies-arrayexpress
GenomicsFoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells (HTS)
We report the androgen receptor recruitment to the chromatin of androgen responsive prostate cancer cell lines, LNCaP-1F5 and VCaP in response to physiological androgen 5a-dihydrotestosterone (DHT) using ChIP-sequencing. We compare the AR recruitment by DHT to that by partial agonist/antagonist cypr...
ORGANISM(S): Homo sapiens 
2013-02-05 | E-GEOD-39879 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of TMPAP viral stable transfected LNCaP cells
To determine the effects produced by the overexpression of transmembrane prostatic acid phosphatase (TMPAP) in viral stable transfected LNCaP cells.
ORGANISM(S): Homo sapiens 
2015-10-02 | E-MTAB-2730 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HeLa CD4+ cells treated with nocodazole and hydroxyurea and transfected with epitope-tagged eTat plasmid sampled at multiple time points
Expression profiles of HeLa CD4+ cells transfected with epitope-tagged eTat plasmid. Cells are treated with nocodazole and hydroxyurea.
ORGANISM(S): Homo sapiens 
2007-09-28 | E-GEOD-571 | biostudies-arrayexpress
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