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ModelsHayer2005_AMPAR_traff_model0
This is model 0 from Hayer and Bhalla, PLoS Comput Biol 2005. It has a bistable model of AMPAR traffic, plus a non-bistable model of CaMKII. This differs from the reference model (model 1) in that model0 lacks degradation and turnover reactions for AMPAR. This model originates from BioModels Data...
2005-01-01 | MODEL9086207764 | BioModels
ModelsHayer2005_simple_AMPAR_traff_model2
This is a highly simplified model of the AMPAR trafficking cycle that exhibits bistability. It is model 2 from Hayer and Bhalla, PLoS 2005. Its main purpose it to illustrate how the bistability arises. This model originates from BioModels Database: A Database of Annotated Published Models (http:/...
2005-01-01 | MODEL9086628127 | BioModels
ModelsHayer2005_AMPAR_traff_model1
This is the basic model of AMPAR trafficking bistability. It is based on Hayer and Bhalla, PLoS Comput. Biol. 2005. It includes the degradation and turnover of AMPARs. The CaMKII portion of the model is not bistable. This model originates from BioModels Database: A Database of Annotated Published...
2005-01-01 | MODEL9086518048 | BioModels
ModelsHayer2005_CaMKII_model3
This is the complete model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 includes PKA regulatory input. This has little effect on the deterministic calculations, but the PKA path...
2005-01-01 | MODEL9086953089 | BioModels
ModelsHayer2005_AMPAR_CaMKII_strong_coupling
This is a model of tight coupling between the AMPAR trafficking bistability, and the CaMKII autophosphorylation bistability. In this model, the CaMKII activity is self sustaining only when AMPAR is turned on. Further, CaMKII turns on when AMPAR is turned on. This model originates from BioModels D...
2005-01-01 | MODEL9087255381 | BioModels
ModelsHayer2005_CaMKII_noPKA_model3
This is the model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 does not include the full PKA regulatory pathway, and instead has a predefined initial amount of active PKA. Th...
2005-01-01 | MODEL9086926384 | BioModels
ModelsHayer2005_AMPAR_CaMKII_weak_coupling
This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of ...
2005-01-01 | MODEL9087474843 | BioModels
UnknownCaveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation
Not available
S-JCBD-201003086 | bioimages
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