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UnknownThe clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eµ-MYC driven B-cell lymphoma.
Not available
S-EPMC4823038 | biostudies-literature
UnknownSignalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.
Not available
S-EPMC6756076 | biostudies-literature
UnknownDiscovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones.
Not available
S-EPMC10150366 | biostudies-literature
UnknownStructure-guided evolution of potent and selective CHK1 inhibitors through scaffold morphing.
Not available
S-EPMC3241339 | biostudies-literature
UnknownStructure-based design of orally bioavailable 1H-pyrrolo[3,2-c]pyridine inhibitors of mitotic kinase monopolar spindle 1 (MPS1).
Not available
S-EPMC3873811 | biostudies-literature
UnknownWhole-genome resequencing of the wild barley diversity collection: a resource for identifying and exploiting genetic variation for cultivated barley improvement.
Not available
S-EPMC12774595 | biostudies-literature
UnknownEfficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico.
Not available
S-EPMC8693692 | biostudies-literature
UnknownClopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
Not available
S-EPMC6193486 | biostudies-literature
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