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To determine the mechanism of cetuximab-resistance in head and neck cancer, a cetuximab-sensitive cell line (SCC1) and its cetuximab-resistant derivative (1Cc8) were analyzed for differentially expressed genes using DNA microarrays. 900 differentially expressed genes were found using the statistical...
ORGANISM(S): Homo sapiens 
Astrocyte-produced HB-EGF limits autoimmune CNS pathology [WGBS]
Astrocyte-produced HB-EGF limits autoimmune CNS pathology [RNA-Seq]
Central nervous system (CNS) resident cells such as microglia, oligodendrocytes and astrocytes are gaining increasing attention in respect to their contribution to CNS pathologies including Multiple Sclerosis (MS). Several studies have demonstrated the involvement of pro- inflammatory glial subsets ...
ORGANISM(S): Mus musculus 
2023-12-01 | GSE245382 | GEO
Central nervous system (CNS) resident cells such as microglia, oligodendrocytes and astrocytes are gaining increasing attention in respect to their contribution to CNS pathologies including Multiple Sclerosis (MS). Several studies have demonstrated the involvement of pro- inflammatory glial subsets ...
ORGANISM(S): Mus musculus 
2023-12-01 | GSE225606 | GEO
LPA is a natural bioactive lipid with growth factor-like functions due to activation of series of six G protein-coupled receptors (LPA1-6). In this study we determine the LPA induced early-gene expression profile in three unrelated human cancer cell lines (MDA-MB-231, MCF7, PC3) with an objective to...
ORGANISM(S): Homo sapiens 
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