Sort   by:  
 Page size 
ProteomicsUncover proteins binding HBV rcDNA
To comprehensively uncover host proteins involved in HBV rcDNA repair, we employed a rcDNA repair system, which can simulate the process of cccDNA formation in vitro. Biotinylated rcDNA first bonds with streptavidin magnetic beads and is then incubated with cell extracts of HepG2-NTCP-K7 cells to fa...
ORGANISM(S): Homo sapiens (Human) 
2024-12-18 | PXD053940 | Pride
Hbv rcdna Dna repair Hepatocytes 
TranscriptomicsNEDD4-binding protein 1 suppresses HBV replication by regulating HBV RNAs
Background and Aims Chronic infection with hepatitis B virus (HBV) has been known to cause liver cirrhosis and hepatocellular carcinoma. Although nucleos(t)ide analogs are mainly used for the treatment of HBV, they require long-term administration and may lead to the emergence of drug resistance. Th...
ORGANISM(S): Homo sapiens 
2025-01-08 | GSE225322 | GEO
GenomicsNEDD4-binding protein 1 suppresses HBV replication by regulating HBV RNAs
NEDD4-binding protein 1 suppresses HBV replication by regulating HBV RNAs
PRJNA935255 | ENA
ProteomicsHBV rcDNA interactome_2023.11.27
Biotin labeled recombinant rcDNA was co-incubated with nuclear extracts of HepG2 and HepG2.2.15 seperately (using non-labeled RrcDNA as control), the interactome were captured by streptavidin coated beads and identified through MS
ORGANISM(S): Homo Sapiens 
2023-11-28 | PXD047306 |
UnknownAND Logic Gate-Based Dual-Specificity DNA Circuit for Isothermal HBV rcDNA Detection.
Not available
S-EPMC12648326 | biostudies-literature
GenomicsSera of individuals chronically infected with hepatitis B virus (HBV) contain diverse RNA types produced by HBV replication or derived from integrated HBV DNA
Sera of individuals chronically infected with hepatitis B virus (HBV) contain diverse RNA types produced by HBV replication or derived from integrated HBV DNA
PRJNA933084 | ENA
TranscriptomicsSera of individuals chronically infected with hepatitis B virus (HBV) contain diverse RNA types produced by HBV replication or derived from integrated HBV DNA
This study aimed to better characterize the repertoire of serum HBV RNAs during chronic HBV infection in humans, which remains understudied. Using RT-PCR, qPCR, RNA-sequencing and immuno-precipitation, we found that (i) >50% of serum samples bore different amounts of HBV replication-derived RNAs (rd...
ORGANISM(S): Homo sapiens 
2023-02-26 | GSE224901 | GEO
UnknownDifferences in sequences between HBV-relaxed circular DNA and covalently closed circular DNA.
Not available
S-EPMC5520316 | biostudies-literature
UnknownScreening of different species reveals cat hepatocytes support HBV infection.
Not available
S-EPMC12333979 | biostudies-literature
UnknownSera of Individuals Chronically Infected with Hepatitis B Virus (HBV) Contain Diverse RNA Types Produced by HBV Replication or Derived from Integrated HBV DNA.
Not available
S-EPMC10062156 | biostudies-literature
Sort   by:  
 Page size