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With the monophasic variant of Salmonella Typhimurium (S. 4,[5],12:i-) emerging as one of the most prevalent serotypes, multidrug resistance has become an increasingly serious clinical challenge. Conventional antibiotic therapy is further constrained by adverse effects, including resistance selec...

2026-10-04 | MTBLS15914 | MetaboLights
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
RNA-seq was used to unveil the molelcualr mechanisms of Cd tolereance in Sedum alfredii Hance shoots
ORGANISM(S): Sedum alfredii 

OBJECTIVE: This study aimed to investigate the plasma metabolic profile of patients with extracranial arteriovenous malformations (AVM).

METHOD: Plasma samples were collected from 32 AVM patients and 30 healthy controls (HC). Ultra-high performance liquid c...

2023-10-30 | MTBLS7753 | MetaboLights
To identify the macrophage binding partner of Mtb BfrB, we selected and purified BfrB tagged with GST, and incubated it with THP-1 lysates before performing GST Pullodwn. Then the eluted protein were examined by sliver stain. Using mass spectrometry, we identified a protein with an apparent molecula...
ORGANISM(S): Homo sapiens (Human) Mycobacterium tuberculosis 
2017-10-17 | PXD006929 | Pride
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