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ProteomicsThe regulator PltZ senses exogenous2,4-DAPG and regulate a novel multidrug resistant pump in involved in Pseudomonas aeruginosaATCC27853
2, 4-diacetylphloroglucinol (2,4-DAPG) is secondary metabolites produced by soil rhizophsere bacterium Pseudomonas fluorescens with ability to against bacteria,fungi, oomycetes and nematodes. Pseudomonas aeruginos is considered to be one cause of nosocomial infection due to its multi-drug resistance...
ORGANISM(S): Pseudomonas aeruginosa LESB58 
2020-01-17 | PXD016202 | Pride
2 Pltz 4-dapg Pseudomonas aeruginosa 
ProteomicsEmhR is an indole-sensing transcriptional regulator responsive for the indole-induced antibiotic tolerance in Pseudomonas fluorescens
Indole is ubiquitously synthesized by plants and bacteria and functions as an inter species signaling molecule to modulate a wide variety of cellular activities. However, it is not clear how the indole signal is perceived and responded by plant growth promoting rhizobacteria (PGPR) at the rhizospher...
ORGANISM(S): Pseudomonas fluorescens F113 
2023-05-04 | PXD016527 | Pride
Efflux pump Antibiotic tolerance Indole 
ProteomicsProteomic analysis reveals the mechanism of different environmental stresses-induced tolerance of Pseudomonas aeruginosa PAO1 to the monochloramine disinfection
Although drinking water disinfection has proved to be an effective strategy to eliminate most waterborne pathogens, bacterial pathogens can still show disinfection tolerance in drinking water distribution systems (DWDSs), posing a great threat to drinking water safety and human health. Despite stres...
ORGANISM(S): Pseudomonas Aeruginosa Pao1 
PXD021907 |
ProteomicsNeutralization mechanism of a HipA-like toxin targeting isoleucyl-tRNA synthetase
HipAB is a type II toxin-antitoxin (TA) system that targets and inactivates specific aminoacyl-tRNA synthetases in response to various stresses. While the molecular targets and neutralization mechanisms of several HipAB-like TA systems have been well characterized, their structural and functional di...
ORGANISM(S): Escherichia Coli K-12 
PXD062828 |
ProteomicsMolecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules
The production of secondary metabolites is one of the major mechanisms for beneficial rhizobacteria to antagonize plant pathogens. However, simultaneously producing large quantities of different secondary metabolites can pose great metabolic burdens and exerts a significant fitness cost on the produ...
ORGANISM(S): Pseudomonas Fluorescens F113 
PXD025403 |
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