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MetabolomicsVolatilomic insight of head and neck cancer via the effects observed on saliva metabolites
Head and neck cancer (HNC) is a heterogeneous malignant disease with distinct global distribution. Metabolic adaptations of HNC are significantly gaining clinical interests nowadays. Here, we investigated effects of HNC on differential expression of volatile metabolites in human saliva. We applied h...
2019-06-03 | MTBLS760 | MetaboLights
TranscriptomicsGene expression profiles of head and neck squamous cell carcinoma
Sage performed on microdissection of Head and Neck tumor, and Head and Neck normal tissue comparative analysis of gene expression profiles of head and neck squamous cell carcinoma and Head and Neck normal tissue
ORGANISM(S): Homo sapiens 
2008-09-30 | E-GEOD-11986 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human head and neck paired diseased squamous cell carcinoma samples vs normal
Forty-four paired (from the same patient) samples of head and neck squamous cell carcinoma (HNSCC) and normal tissue were studied with Affymetrix U95A chips. A stringent multi-test approach, combining 7 traditional and microarray-specific statistical tests, was used to analyze the resultant data. Ca...
ORGANISM(S): Homo sapiens 
2009-02-06 | E-GEOD-6631 | biostudies-arrayexpress
TranscriptomicsMethylationEPIC array from fresh oral and oropharyngeal tissue samples from head and neck squamous cell carcinoma patients, tissue samples from potentially premalignant oral lesions and fresh tonsil tissue samples from control patients
This data was used to detect good biomarkers for head and neck squamous cell carcinoma and was integrated with transcriptome and miRNome data aiming to elucidate role of epigenetics on gene expression in head and neck squamous cell carcinoma.
ORGANISM(S): Homo sapiens 
2024-04-22 | E-MTAB-13954 | biostudies-arrayexpress
TranscriptomicsRNA-Seq count data from fresh oral an oropharyngeal tissue samples from head and neck squamous cell carcinoma patients and fresh tonsil tissue samples from control patients
Integration of transcriptome with miRNome and methylome data aiming to elucidate role of epigenetics on gene expression in head and neck squamous cell carcinoma.
ORGANISM(S): Homo sapiens 
2024-04-22 | E-MTAB-13725 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiling for prediction of chemoradiation efficacy in locally advanced head and neck squamous cell carcinoma
The predictive value of microRNAs for the efficacy of chemoradiation (CRTX) in locally advanced head and neck squamous cell carcinoma (HNSCC) was evaluated. Formalin-fixed, paraffin-embedded tumor material was collected from patients with locally advanced HNSCC treated within the ARO-0401 phase III ...
ORGANISM(S): Homo sapiens 
2017-03-30 | E-MTAB-5198 | biostudies-arrayexpress
TranscriptomicsmiRNA expression in head and neck squamous cell carcinoma (HNSCC)
The involvement of microRNAs (miRNAs) in cancer and their potential as biomarkers of diagnosis, prognosis and response to therapy is becoming increasingly appreciated. The etiology of head and neck squamous cell carcinoma (HNSCC) is predominantly associated with the synergistic effects of tobacco an...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-11163 | biostudies-arrayexpress
TranscriptomicsHNSCC Cells: ctrl vs six tumour lethal miRNAs transfected
Some microRNAs have antiproliferative effects in cells and are believed to act as tumour suppressors. We used a retroviral human microRNA expression library to identify six microRNAs, miR-181a, miR-323, miR-326, miR-342, miR345 and miR-371, that induce antiproliferative effects in head and neck squa...
ORGANISM(S): Homo sapiens 
2013-11-06 | E-GEOD-34881 | biostudies-arrayexpress
TranscriptomicsFN1 expression is a marker of radioresistance in head and neck squamous cell carcinoma
The goal of this project was to analyze differential expression in head and neck cancer cells with various intrinsic radiosensitivity. The gene expression profiles of the cell lines were determined using the Human Genome U133 plus 2.0 Arrays (Affymetrix, Santa Clara, CA). The UTSCC cells were cultur...
ORGANISM(S): Homo sapiens 
2011-06-09 | E-GEOD-21644 | biostudies-arrayexpress
TranscriptomicsmicroRNA-Seq count data from fresh oral an oropharyngeal tissue samples from head and neck squamous cell carcinoma patients and fresh tonsil tissue samples from control patients
Integration of transcriptome with miRNome and methylome data aiming to elucidate role of epigenetics on gene expression in head and neck squamous cell carcinoma.
ORGANISM(S): Homo sapiens 
2024-04-22 | E-MTAB-13953 | biostudies-arrayexpress
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