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Eukaryotic genes are controlled by sequence-specific DNA-binding proteins, chromatin regulators, general transcription factors, and elongation factors. Here we examine the genome-wide location of representative members of these groups and their redistribution when the Saccharomyces cerevisiae genom...
ORGANISM(S): Saccharomyces cerevisiae 
TATA-binding protein (TBP) is central to the regulation of transcription initiation. Recruitment of TBP to target genes can be positively regulated by one of two basal transcription factor complexes: SAGA or TFIID. Negative regulation of TBP promoter association can be performed by Mot1 or the NC2 c...
ORGANISM(S): Saccharomyces cerevisiae 
Monitoring mobilization of transcriptional regulators in response to methyl methanesulfonate and heat shock using ChIP-chip
ORGANISM(S): Saccharomyces cerevisiae 
Failure of molecular chaperones to direct the correct folding of newly synthesized proteins leads to the accumulation of misfolded proteins in cells. HSPA4 is a member of the heat shock protein 110 family (HSP110) that acts as a nucleotide exchange factor of HSP70 chaperones. We found that the expre...
ORGANISM(S): Mus musculus 
An experiment was performed to determine the transcription factor binding site of yeast at room temperature and heat-shock growth conditions.
ORGANISM(S): Saccharomyces cerevisiae 
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