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TranscriptomicsIdentification of an SRF- and androgen-dependent gene signature in prostate cancer
The androgen receptor (AR) is the principal target for treatment of non-organ confined prostate cancer (PCa). Systems and bioinformatics approaches suggest that considerable variation exists in the mechanisms by which AR regulates expression of effector genes and point towards a role for secondary ...
ORGANISM(S): Homo sapiens 
2011-02-28 | E-GEOD-22606 | biostudies-arrayexpress
TranscriptomicsContribution of WDR77 and p53 to androgen response in prostate cancer cells
To decipher the contribution of WDR77 and p53 to androgen-responsive gene expression, effect of siRNA-mediated silencing of WDR77 and p53 on expression of androgen-dependent genes was studied. Human LNCaP prostate cancer cells were transfected with individual siRNA SmartPools targeting WDR77 or p53 ...
ORGANISM(S): Homo sapiens 
2016-03-01 | E-GEOD-66977 | biostudies-arrayexpress
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