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TranscriptomicsHeLa cell response to overexpression of wild type and mutated forms of the P19 splice variant of c-H-ras
The c-H-ras proto-oncogene undergoes alternative splicing of the exon termed IDX giving rise to a novel protein of the Ras family, p19 (H-RasIDX). The experiment tests the effect on the transcriptome of overexpressing the wild type and W164A mutated forms of p19. Keywords: genetic modification Thre...
ORGANISM(S): Homo sapiens 
2009-12-29 | E-GEOD-12059 | biostudies-arrayexpress
ProteomicsA new twist on bacterial motility – two distinct type IV pili revealed by cryoEM
Many bacteria express filaments called type IV pili on their surface, which are involved in motility (twitching), surface adhesion, biofilm formation and DNA uptake (natural transformation). Type IV pili are comprised of a helical assembly of repeating pilin subunits that allow both flexibility and ...
ORGANISM(S): Thermus thermophilus HB27 
2020-03-09 | PXD017353 | Pride
Electron cryo-tomography Flexible filaments Type iv pili Electron cryo-microscopy Pilin 
TranscriptomicsMicroRNA profiling of human HeLa cells overexpressing p19 H-Ras
MicroRNA miRNA expression profiles for human HeLa cells (Cervical cancer), overexpressing p19 H-Ras, were examined to investigate the miRNA regulation by p19 H-Ras. miRNA microarray analysis identified statistical unique profiles, which could discriminate miRNAs regulated by p19 H-Ras and not regul...
ORGANISM(S): Homo sapiens 
2008-12-12 | E-TABM-494 | biostudies-arrayexpress
OtherAnalysis of purified wild type and mutant adenovirus particles by SILAC based quantitative proteomics.
Data from ProteomeXchange, PXD ID: PXD001120. File: 10_2.mzml. Published as part of J Gen Virol. 2014 Aug 5 . From the Abstract: {{i}} We used stable isotope labelling of amino acids in cell culture and high throughput quantitative mass spectrometry to analyse the protein composition of highly puri...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310002885 | GPMDB
Resource Reanalysis 
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