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TranscriptomicsGenome-wide mRNA profiling of adult human pancreatic beta and duct cells in comparison to other human tissues
Aims: establishment of reference samples to investigate gene expression selective for endocrine or ductal-exocrine cells within the adult human pancreas. To this end, human islet endocrine cells, FACS-enriched in insulin+ cells, (n=3) and human exocrine ductal cells (n=2) are compared on Affymetrix ...
ORGANISM(S): Homo sapiens 
2011-07-21 | E-GEOD-30803 | biostudies-arrayexpress
TranscriptomicsPlasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming
Aims/hypothesis: Duct cells isolated from adult human pancreas can be reprogrammed to express islet beta cell genes by adenoviral transduction of the developmental transcription factor neurogenin3 (Ngn3). In this study we aimed to fully characterize the extent of this reprogramming and intended to i...
ORGANISM(S): Homo sapiens 
2012-07-10 | E-GEOD-30802 | biostudies-arrayexpress
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