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ProteomicsStructural and functional fine mapping of cysteines in mammalian glutaredoxin reveal a hierarchy of susceptibility to oxidative inactivation
Protein-S-glutathionylation (PSSG) is a post-translational modification involving the conjugation of glutathione to reactive protein thiols, which can modulate the activity and structure of key cellular proteins. Glutaredoxins (GLRX) are oxidoreductases that regulate this process by performing the r...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD026486 | Pride
Molecular dynamics Glutathione Multiscale modeling Redox S-glutathionylation Quantum mechanics 
TranscriptomicsProgressive human proteinuric nephropathies
We obtained gene-expression profiles of microdissected renal-tubule cells from patients with proteinuric nephropathies. Based on the renal function during follow-up, the patients were divided in stable (n=14) and progressive (n=7) subjects (table 1). The cells of interest were laser-capture microdis...
ORGANISM(S): Homo sapiens 
2008-12-23 | E-GEOD-11513 | biostudies-arrayexpress
UnknownEndothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice.
Not available
S-EPMC6894059 | biostudies-literature
ProteomicsOxidation of peroxiredoxin-4 induces oligomerization and promotes interaction with endoplasmic reticulum proteins
The family of peroxiredoxins catalyzes the reduction of hydrogen peroxide (H2O2). Peroxiredoxin 4 (PRDX4) is the only peroxiredoxin located within the endoplasmic reticulum (ER) and is the highest expressed ER H2O2 scavenger. PRDX4 has emerged as an important player in numerous diseases and its over...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024687 | Pride
Prdx4 Tert-butyl hydroperoxide 
UnknownProtein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways.
Not available
S-EPMC4829300 | biostudies-literature
UnknownInter-rater reliability in performing stifle goniometry in normal and cranial cruciate ligament disease affected dogs: a prospective randomized controlled study.
Not available
S-EPMC11293097 | biostudies-literature
UnknownAre Invasive Group A Streptococcal Infections Preventable by Antibiotic Therapy?: A Collaborative Retrospective Study.
Not available
S-EPMC11407772 | biostudies-literature
UnknownClinical Presentation of Enterovirus D68 in a Swiss Pediatric University Center.
Not available
S-EPMC11542972 | biostudies-literature
ProteomicsLoss of adipose triglyceride lipase aids cancer growth in 3D
Shotgun proteomic analysis of 3D-grown or on CAM-assay grown lung cancer cells lacking or expressing the major triglyceride lipase adipose triglyceride lipase (ATGL)
ORGANISM(S): Homo sapiens (Human) Gallus gallus (Chicken) 
2021-05-21 | PXD021105 | Pride
Lung cancer Atgl Spheroids 
UnknownPertactin deficiency of <i>Bordetella pertussis</i>: Insights into epidemiology, and perspectives on surveillance and public health impact.
Not available
S-EPMC11654710 | biostudies-literature
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