Sort   by:  
 Page size 
TranscriptomicsMYBL2 Is a Sub-haploinsufficient Tumor Suppressor Gene in Myeloid Malignancy (RNAi)
A dosage-dependent role for tumor suppressor genes in the initiation of myeloid malignancies remains controversial. Here we show that MYBL2 is expressed at sharply reduced levels in CD34+ cells from most patients with myelodysplastic syndrome (MDS; 65%; n=26). In a murine competitive reconstitution ...
ORGANISM(S): Homo sapiens 
2013-09-15 | E-GEOD-43400 | biostudies-arrayexpress
TranscriptomicsMYBL2 Is a Sub-haploinsufficient Tumor Suppressor Gene in Myeloid Malignancy (RNA)
A dosage-dependent role for tumor suppressor genes in the initiation of myeloid malignancies remains controversial. Here we show that MYBL2 is expressed at sharply reduced levels in CD34+ cells from most patients with myelodysplastic syndrome (MDS; 65%; n=26). In a murine competitive reconstitution ...
ORGANISM(S): Homo sapiens 
2013-09-15 | E-GEOD-43399 | biostudies-arrayexpress
TranscriptomicsMYBL2 Is a Sub-haploinsufficient Tumor Suppressor Gene in Myeloid Malignancy
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-09-15 | E-GEOD-43401 | biostudies-arrayexpress
TranscriptomicsGene expression profiling upon knockdown of JAK1 in IM9 cells
Natural Killer (NK) cells are primary effectors of innate immunity directed against transformed cells. In response, tumor cells have developed mechanisms to evade NK cell-mediated lysis but the molecular basis for target cell resistance is not well understood. In the present study, we used a lentivi...
ORGANISM(S): Homo sapiens 
2012-06-27 | E-GEOD-37012 | biostudies-arrayexpress
ProteomicsA comparative analysis of the interactomes of viral accessory proteins exploiting DDB1 and Cullin Ubiquitin ligases
Viruses have an ambivalent relationship with the host proteome. While several host proteins are indispensable for replication, detrimental restriction factors need to be antagonized. This process is frequently catalysed by viral accessory proteins which exploit the ubiquitin proteasome pathway, DDB1...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-03-13 | MSV000085095 | MassIVE
Sort   by:  
 Page size