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TranscriptomicsDosage Suppression Genetic Interaction Networks
A functionally diverse subset of yeast temperatures sensitive deletion mutants were transformed with a pool of barcoded yeast ORFs to identify dosage suppressors. Objective: To assess the relative strain proportion after growing DNA barcoded yeast deletion strains in a mixed pools. The barcodes are...
ORGANISM(S): Saccharomyces cerevisiae 
2012-04-21 | E-TABM-1147 | biostudies-arrayexpress
GenomicsMED12L Gene Alterations Define Aggressive BRCA2-Mutant Prostate Cancers
Germline mutation of BRCA2 increases the lifetime risk of developing prostate cancer (PCa) by over 700%. BRCA2-mutant PCa have poorer prognosis than sporadic PCa, with rapid development of metastatic, castrate-resistant prostate cancer (mCRPC) and 5-year cancer-specific survival rates of ~50-60%1-4....
EGAS00001001615 | EGA
GenomicsBRCA_SNV_SR - samples
single nucleotide variant calls from somatic sniper, vcf format. input for subclonal reconstruction
EGAD00001003753 | EGA
GenomicsCPCG BRCA2 - samples
Aligned sequence data from 14 Prostate cancer samples with BRCA2 mutations
EGAD00001002739 | EGA
GenomicsCPCG-BRCA-ARRAY
Raw Array data from the CPCGene BRCA study
EGAD00010001196 | EGA
GenomicsBRCA_SNV - samples
single nucleotide variant calls from somatic sniper, vcf format
EGAD00001003752 | EGA
GenomicsBRCA_SV - samples
structural variant calls from Delly, vcf format
EGAD00001003754 | EGA
GenomicsRNAseq_Landscape
RNAseq reads were aligned with STAR 2.5.3a and gene expression was quantified with RSEM 1.3.0
EGAD00010001703 | EGA
GenomicsA comprehensive assessment of somatic mutation detection in cancer using whole genome sequencing
As whole genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Using tumor-normal sample pairs from two different types of cancer, chronic lymphocytic leukemia and medulloblastoma, we conducted a ...
EGAS00001001539 | EGA
GenomicsICGC Benchmark 1 (CLL) - samples
Raw fastq files from WGS sequencing of CLL and matching blood normal for the ICGC Techval Benchmark1 study. Sequence data was provided to multiple centers for independent analysis and comparison.
EGAD00001001858 | EGA
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