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GenomicsDAC CTC - Plasma-DNA
Data Access Committee EGAC00001000072
EGAC00001000072 | EGA
GenomicsRNA-Seq
Data Access Committee EGAC00001002038
EGAC00001002038 | EGA
GenomicsLiquid Biopsy Data Access Committee
Data Access Committee EGAC00001002239
EGAC00001002239 | EGA
GenomicsInferring expressed genes by whole-genome sequencing of plasma DNA
The analysis of cell-free DNA (cfDNA) in plasma represents a rapidly advancing field in medicine. cfDNA consists predominantly of nucleosome-protected DNA shed into the bloodstream by cells undergoing apoptosis. We performed whole-genome sequencing (WGS) of plasma DNA and identified two discrete reg...
EGAS00001001754 | EGA
Genomicsena-DATASET-MUG-14-07-2016-11:57:14:452-1424 - samples
Single-end sequencing data (trimmed to 60bp) of 104 plasma samples from donors without tumors (male=50; female=54) were merged and used to establish coverage profiles around the TSS and to establish a gene expression prediction algorithm. Dataset includes merged alignements of low coverage whole gen...
EGAD00001002254 | EGA
Genomicsena-DATASET-MUG-24-06-2016-09:50:27:418-334 - samples
RNA-Seq on an Ion Torrent Proton of corresponding tumor material of two metastasized breast cancer patients (Breast7, Breast13).
EGAD00001002216 | EGA
Genomicsena-DATASET-MUG-24-06-2016-10:36:41:861-335 - samples
Merged file of low-coverage WGS from 179 plasma DNA samples from non-cancer controls and cancer patients for assessment of size distribution of plasma nuclear DNA fragments.
EGAD00001002217 | EGA
Genomicsena-DATASET-MUG-24-06-2016-09:45:40:262-333 - samples
Low coverage whole genome sequencing plasma DNA from 50 male, 54 female non-cancer donors. For the analysis of nucleosomal positioning all data from the non-cancer controls were merged. Furthermore, two patients with metastasized breast cancer were sequenced on a NextSeq with higher depth.
EGAD00001002215 | EGA
Genomicsena-DATASET-MUG-26-02-2014-10:25:52:632-26 - samples
In this study we performed whole genome sequencing of plasma DNA (plasma-Seq) of 19 plasma-DNA samples from a total of 10 patients treated with anti-EGFR therapy. We demonstrated that development of resistance to anti-EGFR therapies is frequently associated with focal amplifications of KRAS, MET, an...
EGAD00001000748 | EGA
Genomicsena-DATASET-MUG-29-10-2013-10:52:10:827-14 - samples
In this study we performed ultra deep sequencing of genes associated with anti-EGFR resistance, such as KRAS, BRAF, PIK3CA, and EGFR in 17 plasma-DNA samples from a total of 10 patients treated with anti-EGFR therapy.
EGAD00001000688 | EGA
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