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ModelsHeldt2018 - Proliferation-quiescence decision in response to DNA damage
Heldt2018 - Proliferation-quiescence decision in response to DNA damage This model is described in the article: A comprehensive model for the proliferation-quiescence decision in response to endogenous DNA damage in human cells. ...
2024-09-02 | BIOMD0000000700 | BioModels
ModelsBarr2016 - All-or-nothing G1/S transition
Barr2016 - All-or-nothing G1/S transition This model is described in the article: A Dynamical Framework for the All-or-None G1/S Transition. Barr AR, Heldt FS, Zhang T, Bakal C, Novák B. Cell Syst 2016 Jan; 2(1): 27-37 Abstract: The transition from G1 into DNA replica...
2024-09-02 | BIOMD0000000646 | BioModels
ModelsBarr2017 - Dynamics of p21 in hTert-RPE1 cells
Barr2017 - Dynamics of p21 in hTert-RPE1 cells This deteministic model reveals that a bistable switch created by Cdt2, promotes irreversible S-phase entry by keeping p21 levels low, prevents premature S-phase exit upon DNA damage This model is described in the article: DNA damage during S-...
2024-09-02 | BIOMD0000000660 | BioModels
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