Sort   by:  
 Page size 
ProteomicsSelective Inhibition of MTHFD1/2 in T Cells from Patients with Rheumatoid Arthritis
Ex vivo T cell treatment Immunomagnetic negative isolation was used to obtain untouched human T cells from previously frozen PBMC samples of treatment-naïve (n=6) and MTX-IR (n=3) RA patients (Table S1). The isolated T cells were then cultured and stimulated in a 96-well round-bottom plates for susp...
ORGANISM(S): Homo sapiens (Human) 
2026-04-02 | PXD061849 | Pride
Proteomics Methotrexate Selective mthfd1/2 inhibitor T cells Rheumatoid arthritis 
ModelsJaiswal2017 - Cell cycle arrest
Jaiswal2017 - Cell cycle arrest This model is described in the article: ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration. Jaiswal H, Benada J, Müllers E, Akopyan K, Burdova K, Koolmeister T, Helleday T, Medema RH, Macurek L, L...
2024-09-02 | BIOMD0000000641 | BioModels
UnknownProcessing of protein ADP-ribosylation by Nudix hydrolases.
Not available
S-EPMC6057610 | biostudies-literature
Unknown6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance.
Not available
S-EPMC2913123 | biostudies-literature
TranscriptomicsPARP1- and CTCF-mediated interactions between active and repressed chromatin at the lamina promote oscillating transcription
Transcriptionally active and inactive chromatin domains tend to segregate into separate sub-nuclear compartments to maintain stable expression patterns. However, we have uncovered here an inter-chromosomal network connecting active loci enriched in circadian genes to repressed lamina-associated doma...
ORGANISM(S): Homo sapiens 
2015-08-27 | E-GEOD-26880 | biostudies-arrayexpress
Sort   by:  
 Page size