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TranscriptomicsRole of PsaR of Streptococcus pneumoniae D39 and TIGR4 in global gene expression and virulence
Previous studies have indicated that PsaR of Streptococcus pneumoniae is a manganese-dependent regulator, negatively affecting the expression of at least seven genes. Here, we extended these observations by transcriptome and proteome analysis of psaR mutants in strains D39 and TIGR4. The microarray ...
ORGANISM(S): Streptococcus pneumoniae 
2010-05-15 | E-GEOD-13505 | biostudies-arrayexpress
TranscriptomicsWild type vs glnPA double mutant
This microarray experiment is part of a study addressing the importance of glutamine metabolism in Streptococcus pneumoniae for the virulence of this bacterium. To be able to gain more insight into the phenotype of a double mutant of glnA (TIGR 4 locus tag SP0502, encoding glutamine synthetase) and ...
ORGANISM(S): Streptococcus pneumoniae 
2010-05-26 | E-GEOD-9850 | biostudies-arrayexpress
TranscriptomicsCodY of Streptococcus pneumoniae: link between nutritional gene regulation and virulence
CodY is a nutritional regulator mainly involved in amino acid metabolism. It has been extensively studied in Bacillis subtilis and Lactococcus lactis. We investigated the role of CodY in gene regulation and virulence of the human pathogen Streptococcus pneumoniae. We constructed a codY-mutant and ex...
ORGANISM(S): Streptococcus pneumoniae TIGR4 
2010-05-25 | E-GEOD-7350 | biostudies-arrayexpress
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