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TranscriptomicsTranscriptional Profiling in Non-Human Primates Infected With Lassa Virus to Understand the Immune Response to Lassa Infection
Lassa fever virus (LASV) is a significant human pathogen that is endemic to several countries in West Africa. Infection with Lassa leads to the development of hemorrhagic fever in a significant number of public health cases and it is considered a potential bioweapon. Little is known about the compl...
ORGANISM(S): Macaca fascicularis 
2013-06-18 | E-GEOD-41752 | biostudies-arrayexpress
TranscriptomicsTherapeutics of Ebola hemorrhagic fever: Whole-genome transcriptional analysis of successful disease mitigation
Ebola (EBOV) virus causes severe and often lethal hemorrhagic fever in humans and nonhuman primates (NHP), and has been classified as a Category A bioweapon agent. There are currently no approved preventive vaccines or postexposure treatments for EBOV hemorrhagic fever. The mechanisms of EBOV path...
ORGANISM(S): Homo sapiens 
2010-11-30 | E-GEOD-24943 | biostudies-arrayexpress
TranscriptomicsTranscriptional Profiling of the Immune Response to Marburg Infection
Marburg virus is a genetically simple RNA virus that causes a severe hemorrhagic fever upon infection in humans and non-human primates. The mechanism of how this pathogenesis comes about is not well understood, but it is well accepted that pathogenesis is significantly driven by a hyperactive immune...
ORGANISM(S): Macaca fascicularis 
2015-05-11 | E-GEOD-58287 | biostudies-arrayexpress
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