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ProteomicsTherapeutic targeting of ATR in alveolar rhabdomyosarcoma
Despite advances in multi-modal treatment approaches, clinical outcomes of patients suffering from PAX3-FOXO1 fusion oncogene-expressing alveolar rhabdomyosarcoma (ARMS) remain dismal. Here we show that PAX3-FOXO1-expressing ARMS cells are sensitive to pharmacological ataxia telangiectasia and Rad3 ...
ORGANISM(S): Homo Sapiens (human) 
2022-07-11 | PXD035131 | JPOST Repository
UnknownExtrachromosomal circular DNA promotes inflammation and hepatocellular carcinoma development.
Not available
S-EPMC12533639 | biostudies-literature
UnknownElimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models.
Not available
S-EPMC10985474 | biostudies-literature
UnknownThe effect of adjuvant therapies on long-term outcome for primary resected synovial sarcoma in a series of mainly children and adolescents.
Not available
S-EPMC8557198 | biostudies-literature
UnknownProhibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.
Not available
S-EPMC6693841 | biostudies-literature
UnknownTherapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Not available
S-EPMC9314382 | biostudies-literature
UnknownPre-operative radiotherapy is associated with superior local relapse-free survival in advanced synovial sarcoma.
Not available
S-EPMC10097790 | biostudies-literature
UnknownNegative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma.
Not available
S-EPMC8321661 | biostudies-literature
UnknownPartner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing.
Not available
S-EPMC7275081 | biostudies-literature
GenomicsGenomes of Relapsing Neuroblastoma
Neuroblastoma is a malignancy of the developing sympathetic nervous system that is often lethal when relapse occurs, but the molecular mechanisms behind this process are poorly defined. We here used whole-exome sequencing, mRNA expression, array CGH and DNA methylation analysis to holistically chara...
EGAS00001001387 | EGA
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