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UnknownThe PKG Inhibitor CN238 Affords Functional Protection of Photoreceptors and Ganglion Cells against Retinal Degeneration.
Hereditary retinal degeneration (RD) is often associated with excessive cGMP signalling in photoreceptors. Previous research has shown that inhibition of cGMP-dependent protein kinase G (PKG) can reduce photoreceptor loss in two different RD animal models. In this study, we identified a PKG inhibito...
S-EPMC10607377 | biostudies-literature
ProteomicsAutophosphorylation of conserved yeast and human casein kinase 1 isozymes regulates Elongator dependent tRNA modifications
Casein kinase 1 (CK1) family members are crucial for ER-Golgi trafficking, calcium signaling, DNA repair, tRNA modifications and circadian rhythmicity. Whether and how substrate interactions and kinase autophosphorylation contribute to these diverse cellular processes and CK1 plasticity remains larg...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2024-07-23 | MSV000095414 | MassIVE
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