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UnknownTranslation of a Host Blood RNA Signature Distinguishing Bacterial From Viral Infection Into a Platform Suitable for Development as a Point-of-Care Test.
Not available
S-EPMC7783591 | biostudies-literature
UnknownNanobodies as allosteric modulators of Parkinson's disease-associated LRRK2.
Not available
S-EPMC8892280 | biostudies-literature
MetabolomicsNMR-based metabolic profiling provides diagnostic and prognostic information in critically ill children with suspected infection

Sepsis, defined as life-threatening organ dysfunction caused by infection is difficult to distinguish clinically from infection or post-operative inflammation. We hypothesized that in a heterogeneous group of critically ill children, there would be different metabolic profiles between post-operat...

2020-11-19 | MTBLS563 | MetaboLights
UnknownPhysical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex.
Not available
S-EPMC310739 | biostudies-literature
TranscriptomicsBlood RNA sequencing was performed on a cohort of adults attending the Emergency Department with suspected infection who had subsequently-confirmed viral, bacterial, or no infection diagnoses
The cohort comprised patients recruited between August 2014 - April 2017. It includes patients with bacteremia, positive viral diagnostic test in the context of acute admission and those with no positive microbial diagnostic test, no infection-related ICD-10 diagnostic codes, and no empirical antivi...
ORGANISM(S): Homo sapiens 
2021-08-11 | E-MTAB-10527 | biostudies-arrayexpress
UnknownMechanism of allosteric inhibition in the Plasmodium falciparum cGMP-dependent protein kinase.
Not available
S-EPMC7307193 | biostudies-literature
UnknownBridging a diagnostic Kawasaki disease classifier from a microarray platform to a qRT-PCR assay.
Not available
S-EPMC9988687 | biostudies-literature
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
UnknownHost Transcriptomic Response Following Administration of Rotavirus Vaccine in Infants' Mimics Wild Type Infection.
Not available
S-EPMC7859632 | biostudies-literature
ProteomicsPlasma glycoproteomics delivers high-specificity disease biomarkers by detecting site-specific glycosylation abnormalities
The human plasma glycoproteome holds enormous potential to identify personalized biomarkers to diagnose and understand disease. Recent advances in mass spectrometry and software development are opening novel avenues to mine the glycoproteome for protein- and site-specific glycosylation changes. Here...
ORGANISM(S): Homo sapiens (Human) 
2022-06-01 | PXD034214 | Pride
Glycoproteomics Plasma Glycopeptide Congenital disorders of glycosylation Blood 
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