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MetabolomicsIntegration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis

Molecular networks in neurological diseases are complex. Despite this fact, contemporary biomarkers are in most cases interpreted in isolation, leading to a significant loss of information and power. We present an analytical approach to scrutinize and combine information from biomarkers originati...

2018-08-13 | MTBLS558 | MetaboLights
UnknownSafety evaluation of the food enzyme α-amylase from the genetically modified Bacillus licheniformis strain NZYM-AC.
Not available
S-EPMC10667960 | biostudies-literature
ProteomicsMetformin Impairs Intestinal Fructose Metabolism
Objective: To investigate the effects of metformin on intestinal carbohydrate metabolism in vivo. Method: Male mice preconditioned with a high-fat, high-sucrose diet were treated orally with metformin or a control solution for two weeks. Fructose metabolism, glucose production from fructose, and p...
ORGANISM(S): Mus Musculus (mouse) 
2024-04-27 | PXD041833 | JPOST Repository
UnknownTransgene-product expression levels in genetically engineered breeding stacks are equivalent to those of the single events.
Not available
S-EPMC6592641 | biostudies-literature
UnknownResponse of the metabolic activity and taxonomic composition of bacterial communities to mosaically varying soil salinity and alkalinity.
Not available
S-EPMC10980690 | biostudies-literature
UnknownThe Roles of APOBEC-mediated RNA Editing in SARS-CoV-2 Mutations, Replication and Fitness.
Not available
S-EPMC8722585 | biostudies-literature
UnknownThe roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness.
Not available
S-EPMC9470679 | biostudies-literature
UnknownEarly-Onset Efficacy and Safety Pilot Study of Amphetamine Extended-Release Oral Suspension in the Treatment of Children with Attention-Deficit/Hyperactivity Disorder.
Not available
S-EPMC6362322 | biostudies-literature
TranscriptomicsHematopoietic stem cells from mice treated with G-CSF or saline alone for 36 hours
Recent studies demonstrate that inflammatory signals regulate hematopoietic stem cells (HSCs). Granulocyte-colony stimulating factor (G-CSF) is often induced with infection and plays a key role in the stress granulopoiesis response. However, its effects on HSCs are less clear. Herein, we show tha...
ORGANISM(S): Mus musculus 
2014-02-19 | E-GEOD-55093 | biostudies-arrayexpress
UnknownPyrimidine synthesis enzyme CTP synthetase 1 suppresses antiviral interferon induction by deamidating IRF3.
Not available
S-EPMC11735333 | biostudies-literature
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