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TranscriptomicsSingle-cell transcriptomics of pituitary stem cell-derived organoid model
The pituitary is the master endocrine gland regulating key physiological processes and houses a stem cell compartment. Despite the application of transgenic in vivo approaches, the pituitary stem cells' phenotype, biology, and role remain unclear. To tackle this question, organoids were developed as...
ORGANISM(S): Mus musculus 
2025-01-01 | E-MTAB-14008 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptomics of elderly mouse anterior pituitary in steady-state conditions and after transgenically inflicted local damage
The mouse pituitary gland houses a stem cell compartment which is known to suffer from an inflammatory phenotype at middle age (12-15 months), a process commonly referred to as ‘inflammaging’. Here, we investigate the aging pituitary stem cell phenotype by using single-cell RNA-sequencing interrogat...
ORGANISM(S): Mus musculus 
2025-01-06 | E-MTAB-14067 | biostudies-arrayexpress
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