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TranscriptomicsWhole genome expression after modulation of miR-30a expression
A subset of breast cancer cells displays increased ability to self-renew and reproduce breast cancer heterogeneity (so called, breast tumour-initiating cells or BT-ICs). As microRNAs (miRNAs) control developmental programs in stem cells, BT-ICs may also rely on specific miRNA profiles for their sust...
ORGANISM(S): Homo sapiens 
2013-03-22 | E-GEOD-36565 | biostudies-arrayexpress
TranscriptomicsDNA methylome analysis in infants from The Gambia / Aflatoxin / Seasonality study
Genome wide DNA methylation profiling in infant's blood from a mother/child cohort in The Gambia. The main variables of the analyses were the intra-uterine exposure to aflatoxin B1 (AFB1) and the season of conception. The Illumina Infinium HumanMethylation 450k Beadchip was used to obtain DNA methyl...
ORGANISM(S): Homo sapiens 
2015-04-18 | E-GEOD-59592 | biostudies-arrayexpress
TranscriptomicsMolecular Profiling of Breast Cancer Cells after Gemcitabine exposure
Human breast cancer cell lines were exposed to IC50 gemcitabine (Gemzar) for 24 and 48 hours. RNA was extracted, amplified and hibridized onto Oncochip microarray slides. Human breast carcinoma cell lines MCF7 and MDA-MB-231 were cultured in DMEM with Glutamax-1, supplemented with 10% fetal bovine s...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4937 | biostudies-arrayexpress
TranscriptomicsIdentification of a methylome signature of esophageal squamous cell carcinoma
Background & Aims: Esophageal squamous cell carcinoma (ESCC) is believed to arise from esophageal mucosa through accumulation of both genetic and epigenetic changes. DNA methylation is a critical epigenetic mechanism involved in key cellular processes and its deregulation has been linked to many hum...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-26784 | biostudies-arrayexpress
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
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