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TranscriptomicsGenome-Wide Expression Profiling of human tumor-infiltrating microglia/macrophages
Microglia isolated from glioma patients gain anti-tumor activities upon poly (I:C) stimulation. Expression profiles of human tumor-infiltrating microglia/macrophages before (untreated) and after treatment with poly (I:C) for 48h (induced). Tumor-infiltrating microglia/macrophages were isolated from ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-25289 | biostudies-arrayexpress
TranscriptomicsLOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients
MGMT promoter methylation status is currently the only established molecular prognosticator in IDH wild-type glioblastoma multiforme (GBM). Therefore, we aimed to discover novel therapy-associated epigenetic biomarkers. After enrichment for hypermethylated fractions using methyl-CpG-immunoprecipitat...
ORGANISM(S): Homo sapiens 
2016-03-10 | E-GEOD-74561 | biostudies-arrayexpress
TranscriptomicsWnt secretion protein Evi/Gpr177 promotes glioma tumorigenesis
Silencing of Evi and beta-catenin in U87MG cells
ORGANISM(S): Homo sapiens 
2012-06-29 | E-MTAB-776 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR1 as prognostic biomarkers independent of WHO grade
Meningiomas are frequent central nervous system tumors. Although most meningiomas are benign (WHO grade I) and curable by surgery, WHO grade II and III tumors remain therapeutically challenging due to frequent recurrence. Interestingly, relapse also occurs in some WHO grade I meningiomas. Hence, we ...
ORGANISM(S): Homo sapiens 
2016-02-15 | E-GEOD-74385 | biostudies-arrayexpress
TranscriptomicsMethylation data of 20 samples of human lung adenocarcinoma brain metastases
Methylation status of lung adenocarcinoma brain metastases was analyzed as part of an approach to defining the microenvironment
ORGANISM(S): Homo sapiens 
2020-01-04 | E-MTAB-8660 | biostudies-arrayexpress
TranscriptomicsmRNA microarray data of 63 samples of human lung adenocarcinoma brain metastases
mRNA expression of lung adenocarcinoma brain metastases was analyzed as part of an approach to defining the microenvironment
ORGANISM(S): Homo sapiens 
2020-01-03 | E-MTAB-8659 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics workshop report: quality control considerations from sample preparation to data analysis

The Metabolomics workshop on experimental and data analysis training for untargeted metabolomics was hosted by the Proteomics Society of India in December 2019. The Workshop included six tutorial lectures and hands-on data analysis training sessions presented by seven speakers. The tutorials and ...

2020-12-17 | MTBLS1301 | MetaboLights
GenomicsTranscriptome U87MG TMZ resistant
Transcriptome U87MG TMZ resistant
PRJNA1065845 | ENA
TranscriptomicsGenome-wide copy number analysis of patient-derived gliobastoma cell cultures
Genome-wide copy number variation profiles were analyzed in the patient-derived gliobastoma cell culture samples. For this purpose, gDNA was analyzed using the CytoScan® assay in combination with a one-color based labeling and hybridization protocol. Signals on the CytoScan® HD microarrays were dete...
ORGANISM(S): Homo sapiens 
2019-02-28 | E-MTAB-7649 | biostudies-arrayexpress
Genomicsbe40ebac-acee-4026-a661-4330bb0f657b - samples
Bam files for 124 samples (62 tumor vs blood pairs); Whole Genome Sequencing performed on Illumina HiSeq X Ten
EGAD00001005061 | EGA
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