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TranscriptomicsBreast cancer endothelial interaction
MATERIALS AND METHODS: The genomic effects of tumor-endothelial interactions in cancer are not yet well characterized. To study this interaction in breast cancer, we set up an ex vivo coculture model with human benign and malignant breast epithelial cells with endothelial cells to determine the asso...
ORGANISM(S): Homo sapiens 
2010-02-17 | E-GEOD-20364 | biostudies-arrayexpress
TranscriptomicsGene expression changes in Piloderma croceum-Quercus robur ectomycorrhizal roots compared to Piloderma croceum free-living mycelium
Illumina HiSeq technology was used to generate mRNA profiles from Piloderma croceum ectomycorrhizal roots compared to free-living mycelium . Mycorrhizal roots were harvested after 8 weeks, pooled and used for RNA extraction. Reads of 2X100bp were generated and aligned to Piloderma croceum (http://g...
ORGANISM(S): Piloderma croceum 
2015-02-06 | E-GEOD-63925 | biostudies-arrayexpress
ProteomicsCyclipostins and Cyclophostin analogs impair growth of Mycobacterium abscessus by inhibiting enzymes involved in many physiological processes
Mycobacterium abscessus is nowadays under the spotlight of the scientific community. This pathogenic mycobacteria is indeed responsible for a wide spectrum of infections involving mostly pulmonary infections in patients with cystic fibrosis. M. abscessus is intrinsically resistant to a broad range o...
ORGANISM(S): Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) 
2019-10-08 | PXD014255 | Pride
Anti-mycobacterial agents Total synthesis  drug susceptibility  activity based-protein profiling  proteomics analysis 
UnknownEngineered Bacterial Flavin-Dependent Monooxygenases for the Regiospecific Hydroxylation of Polycyclic Phenols.
Not available
S-EPMC9303722 | biostudies-literature
TranscriptomicsThe tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse
The histone modifying complexes PRC2 and TrxG/MLL play pivotal roles in determining the activation state of genes controlling pluripotency, lineage commitment, and cell differentiation. Long non-coding RNAs (lncRNAs) can bind to either complex, and some have been shown to act as modulators of PRC2 o...
ORGANISM(S): Mus musculus 
2013-01-28 | E-GEOD-43078 | biostudies-arrayexpress
TranscriptomicsDisruption of KCC2 in parvalbumin-positive interneurons causes fatal epilepsy in mice
Since many years, we are interested in the regulation of the intraneuronal chloride concentration. We were the first group reporting a full knockout of the KCl-co-transporter KCC2, which dies immediately after birth due to respiratory failure. Notably, KCC2 loss-of-function mutations are associated ...
ORGANISM(S): Mus musculus 
2022-11-02 | E-MTAB-11147 | biostudies-arrayexpress
UnknownFunctional impairments for outcomes in a randomized trial of unruptured brain AVMs.
Not available
S-EPMC5631171 | biostudies-literature
ProteomicsA jack of all trades and a master of some: remodeling of signaling pathways downstream of CFIm 3’ end processing factor
The mammalian cleavage factor I (CFIm) has been implicated in alternative polyadenylation (APA) in a broad range of contexts, from cancers to learning deficits and parasite infections. To uncover the molecular pathways that translate CFIm expression levels into these observed phenotypes, we carried ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-11 | PXD027034 | Pride
Tmt Phosphorylation Cfim3 
UnknownSimultaneous manifestation of metallic conductivity and single-molecule magnetism in a layered molecule-based compound.
Not available
S-EPMC8162363 | biostudies-literature
UnknownCFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis.
Not available
S-EPMC8989530 | biostudies-literature
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