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TranscriptomicsGene expression profiles of patients with multiple myeloma who have been treated previously
This Series represents the gene expression profiles of patients with multiple myeloma who have been treated previously. In brief, Total Therapy 6 (TT6) is an open label phase 2 protocol for patients with symptomatic multiple myeloma, who had been treated with more than one cycle of prior therapy exc...
ORGANISM(S): Homo sapiens 
2015-01-20 | E-GEOD-57317 | biostudies-arrayexpress
TranscriptomicsThalidomide in Total Therapy 2 Overcomes Inferior Prognosis of Myeloma with Low Expression of the Glucocorticoid Receptor Gene NR3C1
Purpose: Because dexamethasone remains a key component of myeloma therapy, we wished to examine the correlation of baseline and relapse expression levels of the glucocorticoid receptor gene NR3C1 with other clinical features. Experimental Design: We investigated the clinical impact of gene express...
ORGANISM(S): Homo sapiens 
2012-11-05 | E-GEOD-38627 | biostudies-arrayexpress
TranscriptomicsDNA methylation in normal PC, MGUS, SMM and MM
To characterize epigenomic changes during the transformation of normal plasma cells to myeloma, we used the HELP assay to analyze the methylome of CD138+ cells from 56 subjects representing premalignant (MGUS), early and advanced stages of myeloma as well as healthy controls. Plasma cells from prem...
ORGANISM(S): Homo sapiens 
2013-04-03 | E-GEOD-43860 | biostudies-arrayexpress
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