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TranscriptomicsEstrogen response uterine gene profile in Ex3αERKO
WT and Ex3aERKO females were ovariectomized and injected with saline or estradiol. Uterine tissue was collected after 2 or 24 hours. RNA was analyzed by microarray to determine if the Ex3aERKO mice would lack the residual transcritpional resposnes seen in the previous aERKO model. 3 uteri per group ...
ORGANISM(S): Mus musculus 
2010-07-22 | E-GEOD-23072 | biostudies-arrayexpress
GenomicsERM-NM-1 and PolII ChIP seq from Mouse Uterus
To advance understanding of mechanisms leading to biological and transcriptional endpoints related to estrogen action in the mouse uterus, we have mapped ERM-NM-1 and RNA polymerase II binding sites using chromatin immunoprecipitation (ChIP) followed by sequencing of enriched chromatin fragments (Ch...
ORGANISM(S): Mus musculus 
2012-04-08 | E-GEOD-36455 | biostudies-arrayexpress
GenomicsER and RNA PolII ChIP-seq in WT and ER mutant mouse uterus
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-04-04 | E-GEOD-56501 | biostudies-arrayexpress
TranscriptomicsThe transcriptional response of mouse uterus to estrogen is genetically regulated
The growth and development of the uterus in response to 17β-estradiol (E2) is genetically controlled, with marked variation observed depending on the mouse strain studied. Previous work from our laboratory using inbred mice that are high (C57BL6/J; B6) or low (C3H/HeJ; C3H) responders to E2 has led ...
ORGANISM(S): Mus musculus 
2013-06-11 | E-GEOD-38800 | biostudies-arrayexpress
GenomicsERa and PolII ChIP seq from KIKO mouse uterus
ChIP-seq from mice with DNA binding mutations in Esr1 (KIKO mouse). Estrogen Receptor M-NM-1 (ERM-NM-1) interacts with DNA, directly, or indirectly via other transcription factors, referred to as M-bM-^@M-^\tetheringM-bM-^@M-^]. Evidence for tethering is based on in vitro studies and a widely used M...
ORGANISM(S): Mus musculus 
2014-04-03 | E-GEOD-56466 | biostudies-arrayexpress
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