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UnknownBayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC6008104 | biostudies-literature
UnknownActivating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors.
Not available
S-EPMC5456373 | biostudies-literature
UnknownRandomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.
Not available
S-EPMC6085179 | biostudies-literature
UnknownPhase II trial of erlotinib plus concurrent whole-brain radiation therapy for patients with brain metastases from non-small-cell lung cancer.
Not available
S-EPMC3577951 | biostudies-literature
UnknownThe BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC5065110 | biostudies-literature
TranscriptomicsAn epithelial-mesenchymal transition (EMT) gene signature predicts resistance to erlotinib and PI3K pathway inhibitors and identifies Axl as a novel EMT marker in non-small cell lung cancer.
Epithelial/mesenchymal transition (EMT) is associated with loss of cell adhesion molecules, such as E-cadherin, and increased invasion, migration, and proliferation in epithelial cancers. In non-small cell lung cancer (NSCLC), EMT is associated with greater resistance to EGFR inhibitors. However, it...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-33072 | biostudies-arrayexpress
TranscriptomicsExpression profiling of lung cancer cell lines (UTSW Lung Panel V2)
Epithelial/mesenchymal transition (EMT) is associated with loss of cell adhesion molecules, such as E-cadherin, and increased invasion, migration, and proliferation in epithelial cancers. In non-small cell lung cancer (NSCLC), EMT is associated with greater resistance to EGFR inhibitors. However, it...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-32989 | biostudies-arrayexpress
Genomicsena-DATASET-MDACC-20-08-2014-16:58:44:853-680 - samples
This is the targeted capture deep sequencing (TCS) data for validation of the mutations discovered in the WES step. There are 58 bam files of TCS data including 48 tumor samples and 10 peripheral blood WBC samples.
EGAD00001000985 | EGA
Genomicsena-DATASET-MDACC-20-08-2014-16:52:57:923-677 - samples
This is the Whole Exome Sequencing (WES) data from 59 samples from 11 patients with lung adenocarcinomas including 48 tumor samples and 11 peripheral white blood cell samples
EGAD00001000984 | EGA
GenomicsIntra-tumor heterogeneity of localized lung adenocarcinomas defined by multi-region sequencing
Background: Intra-tumor heterogeneity (ITH) may have profound impacts on biopsy strategy, characterization of actionable targets, treatment planning, and drug resistance. ITH of lung cancers has not been well studied. Methods: We performed multi-region whole exome sequencing (average sequencing de...
EGAS00001000930 | EGA
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