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GenomicsGenome-wide analyses of the DRB response of the histone H3 Lys36 methylation state, as well as Ash1l occupancy in mouse embryonic stem cells.
Using wild type and Ash1l ?SET mutant embryonic stem cells, against a prevalent notion, here we report di-,tri-methylation of histone H3 Lys36 occur independently of ongoing transcription. Ash1l ?SET mutant shows the impaired methylation levels in broad range of genome. Intriguingly, data implicate ...
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-48421 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of Ash1l mutant mouse embryonic stem cells.
Using wild type and Ash1l deltaSET mutant embryonic stem cells, here we report differences of gene expression pattern under undifferentiated state and differentiated state. Interestingly, gene expression changes are frequently observed in a subset of gene group that is regulated by Polycomb group pr...
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-48419 | biostudies-arrayexpress
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