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MetabolomicsIdentification of AK4 and RHOC as novel oncogenes addicted by adult T-cell leukemia
Adult T-cell leukemia (ATL) is a highly aggressive T-cell malignancy characterized by human T-cell leukemia virus type 1 (HTLV-1) infection. ATL has a very poor prognosis and lacks satisfactory treatments; therefore, it is critical to identify novel targets in ATL cells in order to develop effective...
2025-02-03 | MTBLS11858 | MetaboLights
MetabolomicsIdentification of AK4 and RHOC as novel oncogenes addicted by adult T-cell leukemia
Adult T-cell leukemia (ATL) is a highly aggressive T-cell malignancy characterized by human T-cell leukemia virus type 1 (HTLV-1) infection. ATL has a very poor prognosis and lacks satisfactory treatments; therefore, it is critical to identify novel targets in ATL cells in order to develop effective...
2025-02-03 | MTBLS11844 | MetaboLights
TranscriptomicsExpression profiling by array in ATLL
Previously, we have shown that an AP-1 family member Fra-2, which is hardly expressed in normal mature T cells, is consistently over-expressed in adult T-cell leukemia/lymphoma (ATLL), and together with JunD, upregulates CCR4 and many other genes including proto-oncogenes c-Myb, MDM2, Bcl-6, and SOX...
ORGANISM(S): Homo sapiens 
2013-05-16 | E-GEOD-38021 | biostudies-arrayexpress
UnknownPrediction of the Sex-Associated Genomic Region in Tunas (Thunnus Fishes).
Not available
S-EPMC8693018 | biostudies-literature
UnknownCooperative Function of Atg8- and TORC1-Mediated Activities in Yeast.
Not available
S-EPMC12511908 | biostudies-literature
TranscriptomicsDevelopment of gene expression signatures for knockdown of synthetic lethal gene
We performed genome-wide expression profiling analysis to define the genes underlying the synthetic-lethal relationship between CBP and p300. We extracted 1,936 genes whose expression levels changed >2-fold upon p300-knockdown (KD) in CBP-KO cells, or upon CBP-KD in p300-KO cells, but not in either ...
ORGANISM(S): Homo sapiens 
2015-12-12 | E-GEOD-73682 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis shoots and roots in response to exogenous H2O2 with differential kinetics
Arabidopsis plants (Col-0) were hydroponically grown for 10 days at 22°C under 30~40 μE·m−2·s−1 and continuous light conditions. Treatment with 100 mM H2O2 or sterile distilled water as mock control by spraying for shoot treatments, or dipping for root treatments. Relationship between treated and ha...
ORGANISM(S): Arabidopsis thaliana 
2019-06-01 | E-MTAB-4961 | biostudies-arrayexpress
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