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TranscriptomicsModeling the clinical phenotype of BTK inhibition in the mature murine immune system
Using the novel BTK inhibitor PF-303, we model the clinical phenotype of BTK inhibition by systematically examining the impact of PF-303 on the mature immune system in mice autoimmune indications. However, our current knowledge of the role of BTK in immune competence has been gathered in the context...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-56483 | biostudies-arrayexpress
TranscriptomicsResponse of Streptomyces coelicolor to treatment with the antibiotics vancomycin bacitracin and moenomycin A
To determine the response at the transcriptional level of S. coelicolor cells to treatment with 3 antibiotics that target distinct stages of cell wall biosynthesis, biological triplicate cultures of strain M600 were treated with sub-lethal concentrations (10 µg/ml) of vancomycin, bacitracin or moeno...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2011-04-29 | E-MEXP-3032 | biostudies-arrayexpress
MetabolomicsDiagnostic utility of clinicodemographic, biochemical and metabolite variables to identify viable pregnancies in a symptomatic cohort during early gestation.

Study question: Can a novel machine learning pipeline create predictive models that identify a composite biomarker to differentiate live normally sited pregnancies (LNSP) from non-viable pregnancies in women presenting with pain and/or bleeding in early gestation?

Summary answer: Serum met...

2025-08-14 | MTBLS6219 | MetaboLights
MetabolomicsThe impact of nutritional supplementation on sweat metabolomic content
Sweat is emerging as a prominent biosource for real-time human performance monitoring applications. Although promising, sources of variability must be identified to truly utilize sweat for biomarker applications. In this proof-of-concept study, a targeted metabolomics method was applied to sweat col...
2021-03-15 | MTBLS2427 | MetaboLights
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
UnknownThe unrestricted global effort to complete the COOL trial.
Not available
S-EPMC10173926 | biostudies-literature
UnknownSafety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial.
Not available
S-EPMC11251612 | biostudies-literature
UnknownInternational Epidemiology of Carbapenemase-Producing Escherichia coli.
Not available
S-EPMC10444003 | biostudies-literature
UnknownEfficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico.
Not available
S-EPMC8693692 | biostudies-literature
UnknownA prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study.
Not available
S-EPMC8576477 | biostudies-literature
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