Despite efficacy of FLT3 and BCL2 inhibition in acute myeloid leukemia (AML), relapse limits survival. Mutation status and AML monocytic differentiation are implicated in resistance. On-treatment tumor evolution may select for genetically distinct clones or shifts in differentiation not resolvable ...
Zinc (Zn) is an essential trace element for all life forms. Zn supplementation has been used to treat diarrheal disease in children, and in the U.S. swine industry at pharmacological levels to promote growth and fecal consistency, but underlying mechanisms explaining these beneficial effects remain ...
This a model from the article:
Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats.
Potter LK, Zager MG, Barton HA. Am J Physiol Endocrinol Metab.
2006:91(5):E952-64. 16757547
,
...
