Cytoplasmic histidyl-tRNA synthetase (HARS1) is an essential protein in translation ligating histidine to its cognate tRNAHis. HARS1 is one of several aminoacyl-tRNA synthetase associated with Charcot-Marie-Tooth Disease, an axonal peripheral neuropathy. Advances in genetic testing identify many var...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)