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ProteomicsInteractions of human norovirus capsid P domain with histo-blood group antigens with Hydrogen-Deuterium Exchange Mass Spectrometry
Attachment of human noroviruses to histo blood group antigens (HBGAs) is essential for infection, but how this binding event promotes the infection of host cells is unknown. Here, we employed protein NMR experiments supported by mass spectrometry and crystallography to study HBGA binding to the P ...
ORGANISM(S): Norwalk virus Norovirus Hu/GII/JP/2015/GII.P17_GII.17/Kawasaki308 Norovirus Hu/GII.4/MI001/2011/USA Norovirus Hu/GII-4/Saga4/2006/JP 
2019-03-20 | PXD011914 | Pride
Hdx ms P domain Gii.4 saga Human norovirus Histo-blood group antigens 
ProteomicsN-glycoproteomic analyses of human intestinal enteroids, varying in histo-blood group geno- and phenotypes, reveal a wide repertoire of fucosylated glycoproteins
Human noroviruses, globally the main cause of viral gastroenteritis, show strain specific affinity for histo-blood group antigens (HBGA) and can successfully be propagated ex vivo in human intestinal enteroids (HIEs). HIEs established from jejunal stem cells of individuals with different ABO, Lewis ...
ORGANISM(S): Homo sapiens (Human) 
2024-04-10 | PXD046494 | Pride
Higher-energy collision dissociation Intestinal epithelium : glycoproteomics Host-pathogen interaction Histo-blood group antigens Human intestinal enteroids Fucosyltransferase Human norovirus Lc-ms/ms 
UnknownStructural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens.
Not available
S-EPMC4894678 | biostudies-literature
UnknownHuman noroviruses' fondness for histo-blood group antigens.
Not available
S-EPMC4338890 | biostudies-literature
UnknownGenogroup IV and VI canine noroviruses interact with histo-blood group antigens.
Not available
S-EPMC4178834 | biostudies-literature
UnknownNorovirus-host interaction: multi-selections by human histo-blood group antigens.
Not available
S-EPMC3149758 | biostudies-literature
UnknownThe histo-blood group antigens of the host cell may determine the binding of different viruses such as SARS-CoV-2.
Not available
S-EPMC7842250 | biostudies-literature
UnknownNorovirus drug candidates that inhibit viral capsid attachment to human histo-blood group antigens.
Not available
S-EPMC5026924 | biostudies-literature
UnknownHisto-Blood Group Antigens, Enteropathogen Carriage and Environmental Enteropathy in Stunted Zambian Children.
Not available
S-EPMC9046470 | biostudies-literature
UnknownHisto-blood group antigens and rotavirus vaccine shedding in Nicaraguan infants.
Not available
S-EPMC6656718 | biostudies-literature
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