Sort   by:  
 Page size 
ProteomicsNon-canonical RNA-binding of the histone lysine demethylase KDM5 through interactions with G-quadruplex sequences
RNA-binding proteins are important regulators of RNA biogenesis and function, and recent work shows that chromatin- and RNA-binding proteins can have regulatory roles in transcription. Several approaches have been developed to predict RNA-binding proteins and to identify them experimentally at large...
ORGANISM(S): Homo sapiens (Human) 
2024-04-11 | PXD050767 | Pride
Histone lysine demethylase kdm5  g-quadruplex  non-canonical rna-binding 
GenomicsKDM5 Lysine Demethylases Are Involved in Maintenance of 3'UTR Length [ChIP-Seq]
We discovered that the Saccharomyces cerevisiae lysine demethylase, Jhd2 (also known as KDM5), recruits 3'UTR processing machinery and promotes alteration of 3'UTR length in a demethylase-dependent manner. Interaction of Jhd2 with both chromatin and RNA suggests that Jhd2 affects selection of polyad...
ORGANISM(S): Saccharomyces cerevisiae 
2016-03-23 | E-GEOD-67211 | biostudies-arrayexpress
GenomicsTargeting Lysine Demethylase 5 (KDM5) in Mantle Cell Lymphoma
Targeting Lysine Demethylase 5 (KDM5) in Mantle Cell Lymphoma
PRJNA1018417 | ENA
GenomicsThe Kdm5c histone demethylase controls enhancer and promoter function.
Here, we show that the Kdm5c/Smcx member of the Jarid1 family of H3K4 demethylases is recruited to both enhancer and core promoter elements in ES and neuronal progenitor cells (NPC). Knockdown of Kdm5c deregulates transcription via a local increase in H3K4me3. While at core promoters the function of...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-34975 | biostudies-arrayexpress
UnknownThe Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila.
Not available
S-EPMC6028249 | biostudies-literature
UnknownKDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Not available
S-EPMC6310147 | biostudies-literature
UnknownThe histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction.
Not available
S-EPMC7945993 | biostudies-literature
UnknownThe histone demethylase Kdm5 controls Hid-induced cell death in <i>Drosophila</i>.
Not available
S-EPMC12101616 | biostudies-literature
GenomicsH3K4me3 ChIP in multiple myeloma MM1S cells in the presence and absence of KDM5-C70
In this experiment we demonstrate the use of an inhibitor of the KDM5 family of histone demethylases, KDM5-C70, on H3K4me3 marks in the multiple myeloma cell line MM1S. KDM5-C70 increases H3K4me3 in a global fashion across the genome. Examination of H3K4me3 mark across MM1S cells treated with eithe...
ORGANISM(S): Homo sapiens 
2016-04-05 | E-GEOD-78206 | biostudies-arrayexpress
TranscriptomicsNO001: Kdm5c controls promoter and enhancer activities
The functional organization of eukaryotic genomes correlates with specific patterns of histone methylations. Regulatory regions in genomes like enhancers and promoters differ in their extent of methylation of histone H3 at lysine-4 (H3K4), but it is largely unknown how the different methylation stat...
ORGANISM(S): Mus musculus 
2013-04-05 | E-GEOD-38862 | biostudies-arrayexpress
Sort   by:  
 Page size