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Tyrosine sulfation is a common posttranslational modification in mammals. To date, it has been thought to be limited to secreted and transmembrane proteins, but little is known about tyrosine sulfation on nuclear proteins.To search for tyrosine sulfation on nuclear proteins, we purified the nucleus ...
ORGANISM(S): Homo sapiens (Human) 
2023-07-13 | PXD043754 | Pride
Melanoma progression is driven not only by oncogenic alterations but also by epigenetic programs that remodel the tumor microenvironment. Heparan sulfate (HS) proteoglycans are extracellular matrix components that control growth factor signaling and cell-matrix interactions, yet how chromatin-associ...
ORGANISM(S): Homo sapiens 
2026-09-18 | GSE317470 | GEO
Melanoma progression is driven not only by oncogenic alterations but also by epigenetic programs that remodel the tumor microenvironment. Heparan sulfate (HS) proteoglycans are extracellular matrix components that control growth factor signaling and cell-matrix interactions, yet how chromatin-associ...
ORGANISM(S): Homo sapiens 
2026-09-18 | GSE313495 | GEO
A non-canonical EZH2/TRIM28 epigenetic axis drives heparan sulfate remodeling and melanoma metastasis
A non-canonical EZH2/TRIM28 epigenetic axis drives heparan sulfate remodeling and melanoma metastasis [ChIP-Seq]
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